Metallic nickel is harmful to human body, and its main functions are as follows:

1 Inhalation of metallic nickel dust can easily lead to respiratory disorder and alveolar hypertrophy. Nickel salt is very toxic, especially nickel carbonyl (carbon monoxide and nickel powder can be formed at high temperature), because it is volatile and soluble in adipose tissue, easy to enter cell membrane, and has strong binding force with protein and nucleic acid.

The lethal dose of nickel to rabbits is 7~ 8 mg/kg. Nickel and its compounds can irritate human skin, mucous membrane and respiratory tract, causing dermatitis, tracheitis and even pneumonia. Animal experiments and crowd observation show that nickel can accumulate in kidney, spleen and liver, and can induce nasopharyngeal carcinoma and lung cancer.

Extended data:

A large number of oral nickel salt drugs are less toxic than nickel directly entering the blood, which will lead to vomiting and diarrhea, acute gastroenteritis and gingivitis. Generally, nickel salt is less toxic, but colloidal nickel or nickel chloride, nickel sulfide and nickel carbonyl are more toxic, which can cause central circulation and respiratory disorders, and make muscles, brains, lungs and kidneys edema, bleeding and degeneration.

Smoking can easily lead to lung cancer. One of the reasons is that nickel is one of the 49 trace elements contained in cigarettes, which can stimulate and damage the lungs and respiratory tract. More importantly, nickel combines with carbon monoxide in smoke to form carbonyl groups.

The incidence of lung cancer in workers exposed to nickel refining is high, which is also the result of nickel pollutants inhaled into human body.

Investigation shows that the nickel content in well water, river water, soil and rocks is positively correlated with the mortality rate of nasopharyngeal carcinoma.

Nickel may also be one of the pathogenic factors of leukemia. The content of nickel in serum of leukemia patients is 2-5 times that of healthy people, and the severity of illness is obviously related to the content of nickel in serum. Therefore, the determination of serum nickel content can be used as an auxiliary index to diagnose leukemia, and can be used to estimate the condition and predict the changing trend.

Nickel is often used in electroplating because of its good corrosion resistance. Nickel cadmium batteries contain nickel.

Mainly used in alloys (formulations) (such as nickel steel and nickel silver) and as catalysts (such as raney nickel, especially for hydrogenation), which can be used to make money. Electroplating on other metals can prevent rust. Mainly used for manufacturing stainless steel and other corrosion-resistant alloys, such as nickel steel, nickel-chromium steel and various non-ferrous metal alloys. Copper-nickel alloy with high nickel content is not easy to corrode.

It is also used as a hydrogenation catalyst and in the preparation of ceramic products, special chemical utensils, electronic circuits, green glass and nickel compounds.

Electrolytic nickel: electrolytic nickel is supported by nickel through electrolysis. Stainless steel and its alloy steels are widely used in aircraft, tanks, ships, radars, missiles, spacecraft, machinery manufacturing in civil industry, ceramic pigments, permanent magnet materials, electronic remote control and other fields.

References:

Baidu Encyclopedia-Nickel