Efficacy: strengthening the body resistance, consolidating the foundation and preserving health.
Through the deficiency of yin and yang, qi and blood, the function of viscera is adjusted, the body's resistance is enhanced, and various weak symptoms are eliminated, so as to achieve the purpose of strengthening the body and restoring health. The action principle of strengthening the body resistance and consolidating the prescription has the following aspects:
First, improve immune function.
According to the observation of modern pharmacological experiments, some pharmacological effects of Fuzheng Guben recipe are related to improving immune function. Its impact is as follows:
Effect of 1. on innate immunity
Some traditional Chinese medicines, such as ginseng, astragalus, acanthopanax senticosus, ganoderma lucidum, Ligustrum lucidum, licorice and so on. It can increase the number of peripheral white blood cells and prevent leukopenia caused by cyclophosphamide in large doses.
Ganoderma lucidum can not only significantly increase the number of white blood cells in normal people, but also increase the number of cells when white blood cells eat, and enhance the phagocytic function of reticuloendothelial system (reticuloendothelial cells, endothelial cells and macrophages are called reticuloendothelial system in medicine) (macrophages are treated after swallowing foreign bodies, such as bacteria and tumor cells), and observe the vitality of macrophages through the clearance rate of foreign bodies in blood. Codonopsis pilosula, Astragalus membranaceus, Atractylodes macrocephala and Ganoderma lucidum all have the function of enhancing macrophage activity.
The immune active components in ginseng are mainly ginsenoside and ginseng polysaccharide. Ginsenosides can obviously activate the phagocytosis of reticuloendothelial system in many animals. If its phagocytosis and clearance ability to inert colloidal carbon particles, Staphylococcus aureus and chicken red blood cells are enhanced, the dosage and administration times can be increased and the effect can be enhanced. In clinical experiments, cyclophosphamide can reduce the immune function of mice, and ginseng polysaccharide and ginseng soap can increase their white blood cells. It can also make macrophage function, hemolysin formation and delayed hypersensitivity return to normal.
2. Influence on acquired immunity
Acquired immunity can be understood as acquired immunity. Many health-preserving Chinese medicines can enhance or regulate cellular immune function, such as Cordyceps sinensis, which can obviously promote spleen proliferation and improve the formation rate of E-knot. Some health-preserving Chinese medicines can enhance and regulate humoral immunity. Humoral immunity is a specific antigen-antibody reaction, which forms antigen-antibody complex, neutralizes exotoxin and defends against infection of some pathogens. Using Astragalus membranaceus alone to prevent colds, whether oral or nasal spray, has a significant effect. After taking the medicine, IgA and IgC (two immunoglobulin cells that inhibit virus) in nasal secretions increased obviously, and the ability of peripheral cells to induce interferon also improved. It consists of Radix Astragali, Radix Saposhnikoviae and Rhizoma Atractylodis Macrocephalae.
Second, enhance the function of cardiovascular system.
Health Chinese medicine has the functions of enhancing myocardial contractility, dilating blood vessels, improving microcirculation, lowering blood pressure, resisting arrhythmia and myocardial ischemia.
Epimedium significantly increased the coronary artery flow in vitro, and increased the myocardial oxygen consumption of rabbits in vivo (that is, the organs of experimental animals are not in vitro) (heart activity is an energy-consuming process, that is, it needs to consume a lot of oxygen. The amount of oxygen consumed by myocardium per unit time is called myocardial oxygen consumption), and it can resist experimental arrhythmia and improve microcirculation.
Therapeutic dose of ginseng (decoction, 3 ~ 9g) can strengthen the contractility of many animals' hearts and slow down the heart rate. Its cardiotonic effect is more obvious when the heart function is insufficient. Polygonum multiflorum Thunb. It has obvious blood lipid lowering effect. Alcohol extract of Polygonum multiflorum Thunb. It can increase the ratio of high-density lipoprotein cholesterol to total cholesterol in animal plasma, reduce the contents of total cholesterol, cholesterol lipid and triglyceride in blood, inhibit the formation of intimal plaque and lipid deposition, and prevent the occurrence and development of atherosclerosis.
Third, improve endocrine regulation function.
Effect of 1. on inferior colliculus-pituitary-adrenocortical axis According to clinical experimental research, it is found that the content of 17- hydroxycorticosteroid in 24-hour urine of patients with kidney-yang deficiency is generally lower than normal, with symptoms of low excitability of inferior colliculus-pituitary-adrenocortical system. After treatment with Wenyang recipe, the above symptoms were obviously improved. For example, repeated administration of Cordyceps sinensis can enhance the function of adrenal cortex, and Cordyceps sinensis and its water extract can increase the cholesterol of kidney and the weight gain of adrenal gland. Cordyceps polysaccharide can increase the plasma ketone content and antagonize the feedback inhibition of cortisone on plasma corticosterone, but it cannot reduce its anti-inflammatory effect.
Taking Buyang Gui You Pill for a long time can make some patients with intractable asthma who have been taking prednisone for a long time stop taking drugs completely, and the curative effect is consolidated.
2. Influence on the pituitary gonad axis of inferior colliculus
Ginseng can increase the release of gonadotropin in the anterior pituitary gland. For female animals, it can accelerate their sexual maturity, shorten estrus (non-* * *), prolong estrus (* * *), increase the weight of uterus and ovary, and increase the secretion of luteinizing hormone. For young male animals, it can increase the weight of testis and accessory testis and increase the diameter of vas deferens. In the laboratory, ginseng can make castrated rats (castration means removing male testicles and female ovaries, commonly known as "castration") mate, increase the number of * * * in the testicles of rabbits, enhance their vitality and prolong their survival time in vitro.
The fluid extract of Epimedium can promote the secretion of * * in dogs and increase the weight of prostate, seminal vesicle and levator ani in mice, so it is considered that the extract of Epimedium has androgenic effect. Hippocampus extract also shows the effect of androgen, which is weaker than Fructus Cnidii and Herba Epimedii, but stronger than Gecko.
3. Effects on other endocrine systems
Some prescriptions for tonifying deficiency, such as warming the kidney, nourishing the tortoise and setting the tortoise and warming the kidney and Gui You pills, have certain protective effects on the thyroid gland of hypothyroidism rats, increasing thyroid follicles, enhancing glucose oxidation and increasing the synthesis and secretion of thyroxine.
Experimental study on insulin release from ginsenoside in vitro. This effect does not depend on the existence of calcium supplementation by cells, nor is it inhibited by adrenal gland, which shows that the mechanism of total ginsenoside releasing insulin is different from glucose. Insulin-like substances extracted from non-saponin parts of ginseng can increase the concentration of insulin in blood and promote the release of insulin from islet cells. In addition, traditional Chinese medicine can also improve or improve the function of patients with deficiency syndrome caused by endocrine gland degeneration or atrophy.
Fourth, anti-aging function.
Ginseng is an effective anti-aging drug. Ginsenoside can obviously prolong animal life and cell life. It can inhibit the activity of oxamine oxidase -B in the brain stem of the elderly and make the level of norepinephrine in the cerebral cortex close to that of young people.
Experiments show that Astragalus can prolong the average life span of silkworm and Drosophila melanogaster, increase the passage times of fetal kidney cells and lung diploid cells in vitro, and prolong the survival time of each generation of cells. Polygonum multiflorum Thunb can prolong the growth cycle of diploid cells of Drosophila melanogaster, make cells grow vigorously, and prolong the average life span and maximum life span of Drosophila melanogaster. Its anti-aging effect is a comprehensive effect of scavenging free radicals and improving immune function. After the elderly take Lycium barbarum, some objective indexes reflecting the functional state of the body in the blood reverse to youthfulness.
The radical scavenging function of verb (verb's abbreviation).
Free radicals can interact with nucleic acids, protein, amino acids, sugars and lipid compounds, which have adverse effects on the body and cause poisoning.
Cistanche deserticola can significantly enhance the activity of erythrocyte superoxide dismutase and reduce the content of lipofuscin in myocardium. Superoxide dismutase (commonly known as SOD) can scavenge free radicals, thus protecting biofilm from free radical damage and delaying aging and occurrence.
The experiment also shows that Polygonum multiflorum Thunb can obviously increase the SOD content in blood, liver and brain tissue of the elderly. If Polygonum multiflorum Thunb is given to one-month-old mice for seven months every other day, it can obviously resist the decline of SOD and keep it at the level close to that of two-month-old mice, thus accelerating the elimination of superoxide radicals in the body, reducing the generation of lipid peroxide products, and playing an anti-injury and anti-aging role. In addition, ginseng, angelica and astragalus also have anti-free radical effects.
Sixth, improve the function of digestive system.
Health-preserving Chinese medicines, especially those for invigorating spleen and benefiting qi, can regulate intestinal tension, promote food absorption and regulate autonomic nerves, thus improving the function of digestive tract.
Ginseng can stimulate appetite, and Codonopsis pilosula has obvious anti-experimental gastric ulcer and gastric mucosal injury, and can obviously inhibit gastric acid secretion. Yin-tonifying drugs can improve the decrease of saliva volume, decrease the excitability of sympathetic nerve, increase the tension of vagus nerve, promote gland secretion and improve substance metabolism in patients with yin deficiency, thus increasing the content of digestive enzymes.
Ganoderma lucidum can stimulate appetite and improve gastrointestinal function. Huangqi Jianzhong decoction has inhibitory effect on normal smooth muscle, especially on gastrointestinal smooth muscle under abnormal excitement. Buzhong Yiqi decoction has a two-way regulation effect on small intestine, and has an inhibitory effect on small intestine peristalsis, which slows down its peristalsis and reduces its tension. When the small intestine is in a state of inhibition, its peristalsis is enhanced. It is also found that Cimicifuga foetida and Bupleurum chinense can enhance the action intensity of other drugs, which seems to have a synergistic effect, especially on intestinal peristalsis.
Seven, regulate the function of the nervous system
In the nervous system, people who are weak or defective usually show low function and disorder. In the central nervous system, every exciting activity in the cerebral cortex of patients with yin deficiency is dominant; People with yang deficiency are more likely to see inhibitory activities. In autonomic nervous system, patients with yin deficiency are mainly excited by sympathetic nerve, while patients with yang deficiency are mainly excited by parasympathetic nerve. Fuzheng recipe can improve its function and restore its relative balance by regulating nerve excitation and inhibition.
Pharmacological research shows that ginseng can strengthen the excitement process of cerebral cortex, improve cell nutrition, promote and delay the decline and atrophy of brain, so the ancients thought that ginseng can be "enjoyable and educational" and "unforgettable". Another experiment proves that ginseng also has a certain influence on the inhibition process, so it can "calm the nerves and settle down". Paeonia lactiflora and Paeonia lactiflora. Radix Paeoniae Alba for injection. Entering the ventricle of experimental mice can obviously prolong the sleep time caused by barbital sodium, and inject the alcohol extract of Paeonia lactiflora. It can also prolong the sleep time caused by pentobarbital sodium.
Eight, promote the function of hematopoietic system
Medical experiments show that donkey-hide gelatin, a blood-enriching drug, can accelerate the recovery of blood volume and red blood cells in anemia caused by massive bloodletting, and its curative effect is better than adding iron to milk powder. Pigskin glue can increase the number of platelets and can be used to prevent and treat primary and secondary diseases. Spatholobus Spatholobus Decoction can enrich blood and increase white blood cells in experimental anemia of rabbits. It has a long-term effect on leukopenia caused by radiotherapy, and the effect is quick. Generally, the white blood cells begin to rise 4 days after taking the medicine, but it is best to take the medicine when the white blood cells just drop. If it drops below 0, the effect is not good. After taking a certain dose of pilose antler powder orally or injecting pilose antler essence for a period of time, red blood cells, hemoglobin and reticular red blood cells all increase, and a larger dose can promote the regeneration of blood cells (especially red blood cells).
Nine, improve the function of urinary system
Medical experiments show that Huangqi decoction has diuretic effect on animals, and it lasts for a long time, and it does not produce drug resistance for 7 consecutive days; Atractylodes macrocephala, Rehmannia glutinosa, Angelica sinensis, Eucommia ulmoides, etc. It also has a certain diuretic effect. On the contrary, ginseng has antidiuretic effect, similar to deoxycorticosterone, which may be due to the increase of aldosterone secretion, resulting in sodium retention and decreased urination; Glycyrrhizin contained in Glycyrrhiza uralensis Fisch also has antidiuretic effect. With the decrease of sodium excretion, potassium excretion also decreased slightly. For the experiment of adrenalectomy, glycyrrhizin can still reduce the excretion of sodium and potassium, which shows that this effect is achieved through adrenocortical hormone. For those who warm and tonify kidney-yang, edema symptoms were relieved, urine volume increased and edema gradually subsided after taking medicine for two weeks.
X. Improve the function
Fuzheng drugs can improve the function, which is manifested by adjusting autonomic nerve dysfunction, thus affecting gland secretion and relaxing bronchi; Improve the function of adrenal cortex and reduce the permeability of tissue to blood vessels; Improve the body's defense ability; It has the effects of strengthening the heart. For example, the infusion of cordyceps sinensis, a yang-tonifying drug, has obvious dilating effect on bronchial smooth muscle and can enhance adrenaline; It has inhibitory effect on staphylococcus, etc., and also has inhibitory effect on avian tuberculosis. The antitussive effect of oral glycyrrhetinic acid disuccinate is similar to codeine, but its principle of action has nothing to do with anti-inflammation, but is produced through the central nervous system. In addition, licorice can also promote the secretion of throat and bronchial glands, make sputum easy to cough up, and play an expectorant role.
Dietary taboos when eating traditional Chinese medicine
Chinese medicine pays attention to "harmony", and it is really necessary to "distinguish food" during eating Chinese medicine.
If Chinese medicine is used to treat heat, it is advisable to eat foods with a flat cold nature and avoid warm and dry foods that hurt yin, such as ginger, garlic, pepper, litchi and mutton.
If you have chills, you should eat warm food. Avoid cold food, such as mung beans, bitter gourd, watermelon, Sydney, taro, melon and so on.
People with yang deficiency should warm up, avoid cold and cold, and should not eat cold fruits, cold dishes and food; People with yin deficiency should be nourishing and mild, and should not eat all spicy foods, such as onions, wine, garlic, peppers and ginger. Patients with deficiency syndrome often have decreased spleen and stomach function, and it is not easy to eat greasy, fried and hard food. It is advisable to use light and nutritious food.
Patients with edema avoid salt; Patients with swelling, pain and toxic heat should avoid eating fish, shrimp and spicy food.
Tips: The method of strengthening the body resistance can adjust the function of zang-fu organs, enhance the body's disease resistance, eliminate all kinds of weak symptoms, and achieve the purpose of strengthening the body and restoring health through the deficiency of yin and yang and qi and blood. When taking traditional Chinese medicine, we should also pay attention to some taboo foods, otherwise it will destroy the medicinal properties.