Huangdi Neijing is divided into Lingshu and Suwen, which is the earliest medical classic in China and one of the four classic works of traditional medicine (the other three are Difficult Classic, Treatise on Febrile Diseases and Shennong Herbal Classic).

Huangdi Neijing established the theories of Yin-Yang and Five Elements, Zangxiang, Etiology, Health Preservation, Pharmacology and Meridian in Huangxue. Discussing medicine with a holistic view presents a "holistic medical model" of nature-biology-psychology-society. It is the most influential medical work in China, and is called the medical ancestor.

Shennong Herbal Classic, also known as Herbal Classic or Benjing, is one of the four classic works of Chinese medicine. As the earliest extant classic of traditional Chinese medicine, it originated from Shennong family and was handed down from generation to generation. It was compiled into a book in the Eastern Han Dynasty, but it was not completed at the moment, and the author was different. Many medical scientists in Qin and Han dynasties collected, summarized and compiled the monographs on pharmacological experience at that time, which was the first book in China to systematically summarize traditional Chinese medicine. Most theories and compatibility laws of TCM and the principle of "seven emotions in harmony" have played a great role in the practice of medication for thousands of years and are the source of the development of TCM theory.