Previously, it was thought that vitamin C had little toxicity, even if it was taken orally in excess, it would only cause slight nausea, vomiting, diarrhea and so on. However, in recent years, clinical observation and animal experiments have proved that long-term overdose of vitamin C will lead to a series of adverse reactions.

1, taking a large dose of vitamin C can change the regulation mechanism of vitamin C in the body, accelerate the decomposition and excretion of vitamin C, and once it is stopped, it can lead to withdrawal reaction and early scurvy symptoms, such as swollen gums, bleeding and loose teeth.

2. Using large doses of vitamin C in growing children will make children prone to bone diseases in the future.

3, daily oral vitamin C4 grams, a week later, there may be urinary calcium oxalate stones and kidney calculi.

4. High dose of vitamin C can resist the anticoagulant effect of heparin and dicoumarin, leading to thrombosis.

5. Intake of high-dose vitamin C can increase the urine volume, because its reducibility can produce false positive reaction of urine sugar, which hinders the diagnosis and treatment of diabetic patients and accurately grasps the dosage of hypoglycemic drugs.

6. High dose of vitamin C will reduce female fertility and affect embryo development. The results of animal experiments show this phenomenon very clearly.

7. When the dose of vitamin C exceeds 3 grams per day, it will lead to an increase in intestinal peristalsis, causing abdominal cramps and diarrhea.

8, vitamin C and food containing vitamin B 12 are ingested at the same time, which will destroy a considerable amount of vitamin B 12, and after a large amount of vitamin B 12 is destroyed, people are prone to anemia. ?

2. Adults need to take vitamin C 100mg every day, and the maximum tolerable intake is 1000mg/ day.

Third, it is not recommended to supplement vitamin C normally. Eating more fruits and vegetables rich in vitamin C can completely meet the needs of the human body. ?

Extended data:

Drugs that cannot be taken with vitamin C.

1, aspirin. Fang Fang, the pharmacist in charge of the pharmacy department of anzhen hospital affiliated to Capital Medical University, said that aspirin and vitamin C are both acidic drugs, and taking them at the same time will inhibit the excretion of each other. ?

Aspirin, as a cardiovascular drug, has little effect when taken together with vitamin C in a small dose, but if it is used as an analgesic in a large dose, vitamin C should be taken first, and the dose can be appropriately increased, and the two should be taken two hours apart.

2. Sulfonamides. Vitamin c is an acidic substance. Sulfonamides and their metabolites are easy to produce sulfonamide crystal salts in acidic environment, which leads to urinary calculi and damages the kidneys. If you must take it with vitamin C, it is best to take it every two hours.

3, folic acid. Taking vitamin C together with folic acid will inhibit the absorption of folic acid in the gastrointestinal tract, and taking a large amount of vitamin C will accelerate the excretion of folic acid and weaken the efficacy. So you can take folic acid first, and then take vitamin C two hours later.

4. Some anticoagulant drugs. Vitamin C will affect the anticoagulant effect of heparin and warfarin, shorten prothrombin time and weaken the effect of anticoagulant drugs. Heparin drugs are mainly used in hospitals, but many patients will take warfarin at home, and taking a large amount of vitamin C will have adverse reactions, so pay attention to the interval of medication.

References:

People's Network-Excessive vitamin C is harmful

Baidu encyclopedia-vitamin c

People's Network-Victoria C has many "nemesis"

People's Daily Online-Experts remind: You should not take too much vitamin C.