The manufacturer's suggestion is 10 hour. In actual use, I feel that the replacement time will vary from person to person. For example, some people have tender skin and can change it in 8 hours, while others have strong skin tolerance and can change it in 24 hours. I have done experiments, and the longest effective period of plaster can reach 3 days, so don't waste it. You can put it on at night, take it off during the day and use it repeatedly.
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