1. You can take the D2 194 train in yichang east railway station, which takes 5 hours and 6 minutes, get off at Nanjing South Railway Station, take a bus from Nanjing South Railway Station to Nanjing Bus Terminal, and get off at Huangshan Scenic Area, which takes 4 hours and 30 minutes.
2. You can also drive. Baidu map shows that Yichang is located in the southwest of Hubei Province and Huangshan is located in the south of Anhui Province. The distance between them is 874.0 kilometers. It takes 9 hours and 45 minutes by car, passing through Shanghai-Chongqing Expressway and Beijing-Taiwan Expressway.