After hundreds of years of evolution, the ingredients of this decoction are constantly updated, but its core ingredient "ginseng" has been preserved. In the Han Dynasty, this decoction began to be widely used to relieve fatigue. In particular, senior civil and military officials who are busy all day regard this decoction as a "secret recipe for health preservation". Everyone adds different precious medicinal materials to it, but the core ingredient is basically ginseng.

At the end of the Eastern Han Dynasty, Hua Tuo, an imperial doctor, upgraded and improved this secret recipe for health preservation, and made a decoction with ginseng, medlar, Alpinia oxyphylla and licorice as the main raw materials. It is found that it can not only relieve fatigue, but also invigorate qi and nourish blood, clear heart, improve intelligence and strengthen body, so it is suitable for long-term use. People who insist on taking this "boiled drink" for a long time are generally not too sick, full of blood, full of energy and long life. People call this kind of drink Hua Tuo "the skill of nourishing essence and brain" and "the skill of immortals". In a word, this formula laid the practical foundation of Longli beverage today.