Take Niuhuang Jiedu tablets when you get angry.
Take vitamin E for anti-aging beauty.
……
In life, there are some "magic drugs" and "panacea" that we consider, and we should take a little when we have a headache and brain fever.
However, these drugs have been abused by us!
Ribavirin, also known as "Ribavirin", is a name that many people mistakenly think is a universal antiviral drug. Even many clinicians don't know enough about ribavirin.
Clinically, especially at the grass-roots level, the abuse of ribavirin is serious, such as cold, hand, foot and mouth disease, rotavirus enteritis and so on. Many doctors will choose to use ribavirin. But in fact, ribavirin does not have these related effects.
"Many people don't know enough about ribavirin, so that it has become one of the hardest hit areas for drug abuse." Chen Yue, the pharmacist in charge of pharmacy department of Peking University People's Hospital, told Health Times in July, 20 19 that according to the instructions of ribavirin, ribavirin is mainly used to treat viral diseases such as viral pneumonia, bronchitis and skin herpes virus infection caused by respiratory syncytial virus. ①
Although colds are mostly caused by virus infection, antiviral treatment will not shorten the course of disease. Chen Yue pointed out that in 20 12, the Chinese Medical Doctor Association published "Experts' Standardized Diagnosis and Treatment Knowledge on the Common Cold", which clearly pointed out that "at present, there is no specific antiviral drug for the common cold, and it is not necessary to use antiviral drugs to treat the common cold. Excessive use of antiviral drugs significantly increases the risk of related adverse reactions. "
"Children should use ribavirin with caution. This antiviral drug is also harmful to normal cells and has great risks. " Chen Yue mentioned that there is no need to use ribavirin for many self-limited diseases, such as colds and hand-foot-mouth disease, which can be cured without complications.
For children and adults, the most obvious side effect is easy to cause hemolytic anemia. Hemoglobin decreased within 1~2 weeks after oral treatment, and about 10% patients may be accompanied by cardiopulmonary side effects. ①
When I get angry, I think of Niuhuang Jiedu tablets, such as sore throat, oral ulcer and constipation. Specializing in all kinds of "fire poison". However, Niuhuang Jiedu tablets also have many taboos, and you can't eat them if you want.
Chen Guoming, deputy director of the Pharmacy Department of Zhong Da Hospital affiliated to Southeast University, pointed out in the Health Times article in September, 20 15 that Niuhuang Jiedu Tablet contains bezoar, realgar, gypsum (calcium sulfate), borneol, rhubarb, scutellaria baicalensis, platycodon grandiflorum and licorice. Although there are not many ingredients, it is not suitable for compatibility with Niuhuang Jiedu tablets and some western medicines. Such as aspirin and antacids; Central depressants; Cardiac glycosides such as digitalis and digoxin; Sulfonamides, aminoglycoside antibiotics, etc.
In addition, in 20 19, the state administration of pharmaceutical products revised the instructions for Niuhuang Jiedu preparation, and clearly added the warning that "this product contains realgar, so it is not suitable for excessive or long-term use".
Dr. Chen Guoming suggested that it is best not to take Niuhuang Jiedu tablets for more than 3 days continuously, because it is very strong and not suitable for the elderly, young people or weak patients. ②
Many people think that Angong Niuhuang Pill is a "magic medicine". "Take one pill every once in a while" can "clear away heat toxin in the body and keep the body safe", and even think that taking one pill every month can prevent stroke. Others take Angong Niuhuang Pills for health care in the four solar terms of winter solstice, fright, summer solstice and first frost.
Li Tao, chief physician of the Department of Encephalopathy, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, told Health Times in April 20 12 that cinnabar (mainly mercury sulfide) and realgar (mainly arsenic disulfide) are two dangerous drugs. The former has sedative and tranquilizing effects, while the latter has detoxification effects. However, long-term use of cinnabar and arsenic may cause a small amount of soluble mercury and arsenic to be absorbed by human body, which may have certain chronic toxic and side effects on kidney and blood system.
The toxicity of cinnabar and realgar has been affirmed in the field of traditional Chinese medicine. Pharmacopoeia 20 10 points out that cinnabar is toxic, although it has the effects of clearing away heart fire, calming the nerves and detoxifying, and it is not suitable for long-term use in large or small quantities. However, arsenic in realgar can produce toxic and side effects on various systems of the body, so it should be used with caution. ③
"Nothing can resist the temptation of three tablets a day." In the impression of many people in China, Anakin is a regular antipyretic at home, which is cheap and easy to use.
However, this national best-selling "antipyretic" has been banned from sale, withdrawn from the market or restricted in use in nearly 30 countries such as the United States, Australia, Norway and the Philippines because of its fatal side effects. At present, it is mainly used for animals in Europe and America.
Studies have shown that the clinical application of Anemone may cause the risk of leukopenia and granulocytopenia, and may also cause aplastic anemia, autoimmune hemolytic anemia, urticaria, exfoliative dermatitis and other diseases, among which fatal granulocytopenia is the most serious side effect. The Adverse Drug Reaction Information Bulletin issued by China National Adverse Drug Reaction Monitoring Center has repeatedly involved this drug. ④
On March 17, 2020, the State Administration of Medical Supplies issued an announcement to stop the production and sale of Anemone, including various dosage forms, or to modify the instructions to provide patients with stricter warnings.
Zou Xianbiao, director of the Department of Dermatology and Sexology of the Fourth Medical Center of the General Hospital of the People's Liberation Army, pointed out in the Health Times article of October 2016 10 that some manufacturers of vitamin E will mainly be beauty beauty, emphasizing that vitamin E can effectively fight free radicals, inhibit the production of lipid peroxides, and eliminate chloasma. Without talking about or rarely talking about side effects, this has led many women who love beauty to take vitamin E orally for a long time.
Zou Xianbiao said that if the daily dosage of vitamin E exceeds 800mg, it may be manifested as tenderness in the gastrocnemius and deep vein of the hip, accompanied by edema of the lower limbs. Taking large doses of vitamin E will lead to platelet aggregation and formation, which will lead to thrombophlebitis or pulmonary embolism, or both. ⑤
"How about Pidotimod? Many doctors recommend it to enhance immunity. Pidotimod is said to enhance immunity. All husbands, mothers and mother-in-law require their children to drink it ... Pidotimod often appears when children are sick. It used to be the "children's medicine" in parents' minds.
20 17- 12, Ji Lianmei, a well-known pharmacist, published an article in his personal account, saying that the annual sales of pidotimod in China is about 4 billion yuan, but it is suspected of abuse, and the clinical efficacy and safety of the drug are still unclear. The indications in Pidotimod's instructions include urinary system infection, gynecological infection, eczema and urticaria besides cold, fever and cough.
Pidotimod is an immunomodulator. According to the description of the drug packaging box, it is suitable for all kinds of patients with low immune function, including recurrent upper and lower respiratory tract infections, otolaryngology, urinary system infections, gynecological infections, etc., and can be used to prevent acute infections, shorten the course of disease, and reduce the severity of the disease, as an auxiliary drug for acute infections.
Zheng Fei, the pharmacist in charge of pharmacy department of Oriental Hospital of Beijing University of Chinese Medicine, said in an interview with Health Times, "At present, there is a shortage of drugs for children in China, and the level of research and development and pharmacy is very low, and the data of clinical experiments are also very few. In this case, Pidotimod publicly stated in the instructions and efficacy propaganda that it has a good preventive or therapeutic effect on recurrent respiratory tract infections, asthma, urinary tract infections and gynecological infections, which is easy for parents to feel that this is a panacea. " ⑥
On March 9, 20 18, China Food and Drug Administration and China issued a notice to revise the instructions of pidotimod, and decided to revise the instructions of pidotimod preparation, making it clear that children under 3 years old are prohibited. In terms of indications, it is clearly defined as "adjuvant treatment of chronic or recurrent respiratory tract infections and urinary tract infections." In terms of usage and dosage, the instructions set a limit of 60 days for both children and adults.
2065438+On March 20th, 2008, the State Food and Drug Administration of the United States issued a document, requiring relevant production enterprises to start clinical efficacy trials as soon as possible, and report the evaluation results to the Drug Evaluation Center within three years.
This article is synthesized from:
①20 19-07-05 health times "ribavirin cheated many people"
②20 15-09-2 1 Health Times "Niuhuang Jiedu Tablets can't be eaten casually"
③2020-07- 10 Health Times "Angong Niuhuang Pill as a Health Care Product for Emergencies"
④ On March 20th, 2020, Health Times reported that the antipyretic analgin had reached a desperate situation.
⑤ 2016-1-15 Health Times "Beauty Don't Abuse Vitamin E"
⑥20 18-0 1-09 Health Times "Suspected Abuse of Children Pidotimod"