Holding urine is extremely harmful. Frequent urination will increase the pressure in the bladder, causing urine to flow back to the kidney, which is easy to cause pyeloureteritis. In addition, it will make the bladder wall thinner, which is easy to cause chronic inflammation of the bladder. Because the bladder is adjacent to the prostate, inflammation can gradually spread to the prostate, causing chronic inflammation of the prostate. Chronic prostatitis brings great pain to patients, and also brings difficulties to the treatment of prostatitis. Prostate "likes cold and is afraid of heat". It is easy to cause prostate disease when urinating in cold. Prostate is the most typical organ that likes cold and fears heat. It guards the human reproductive system, secretes antibacterial factors and protects itself and the urinary tract. However, the prostate is located at the crossroads of urinary system, reproductive system and rectum, and its growth environment is harsh, and it is at the end of the body. Often affected by surrounding diseases, such as bacteria and other germs directly invading or bacteria invading through blood or lymphoid tissue. These pathogens are deposited in the prostate for a long time, and once the immune function declines, they will develop into various prostate diseases. In low temperature environment, the excitability of prostate sympathetic nerve will be significantly enhanced, which will make the prostate contract, cause chronic congestion and increase the pressure in urethra. Holding the urine will make the bladder full, oppress the prostate, aggravate the deposition of prostatic fluid, lead to the onset of prostate diseases, and make patients have symptoms such as frequent urination, urgency, nocturia, dysuria, perineum and testicular pain. Pay attention to keep warm in winter to prevent prostate diseases. Male friends should develop good living habits, try not to eat spicy and stimulating food, quit smoking and drinking, and reduce inducing factors. Don't sit for a long time, don't hold your urine, and change your clothes in time according to the temperature to avoid catching cold.