Su Wenbao's Theory of Quan Ming Xing said: "Life is tangible and cannot be separated from Yin and Yang." This shows that human life activities are based on yin and yang in the body, and yin and yang in the body must adapt to the alternation of yin and yang in nature, so that life activities can be carried out normally. Therefore, "Su Wen is angry with Heaven" also said: "Yin people, hiding essence, also; Yang, guarding the outside world, is also solid ... It is based on saints and Yang, with harmonious tendons and veins, strong bone marrow and qi and blood coming from it. If so, internal and external harmony, evil can not be harmed. " In other words, not only the internal yin and yang should be reconciled, but also the external yin and yang should be kept in harmony and balance. Therefore, "Su Wen Nu Tian" further emphasizes: "Where Yin and Yang are heavy, Yang is solid. The two are not harmonious, if there is no autumn in spring and no summer in winter; Therefore, harmony is sacred, so it cannot be hidden, yin is absolutely, yin is hidden, and spirit is the rule. "

In short, emphasizing the balance of Yin and Yang, coordinating the internal and external environment, people will be healthy, not sick, not easy to age and prolong life. But with the growth of age, the yin and yang in the human body gradually lose balance, and people gradually get older. For example, Huangdi Neijing said: "Forty years old, but Yin Qi's self-esteem is also poor." "A Thousand Daughters Must Be Prescribed" also points out: "When a man is over 50, the sun's qi will decline, which will damage the sun and his heart will gradually retreat. If you forget the past and lose the future, you will live happily. Thus, the imbalance between Yin and Yang and Yang Can leads to aging, and regulating Yin and Yang has anti-aging effect. For example, "Su Wen's Theory of Yin and Yang should be like images" said: "If you can know seven losses and eight benefits, then two can be adjusted. If you know how to use this, you will be precocious. "

Traditional Chinese medicine believes that regulating the yin and yang of the kidney has the function of regulating the yin and yang of the whole body, so it has the function of anti-aging and prolonging life. Modern medicine believes that the central nervous system has a high degree of adaptability and perfect regulatory function, which promotes the body to adapt to its environment. That is, the "correspondence between man and nature" in traditional Chinese medicine. However, if the age-related changes originate from the nervous system itself, then this change is the decisive factor of the aging of the body. So some people say that human aging is caused by the destruction of self-regulation mechanism and the primary change of genetic device.

The changes of hypothalamic nuclei are of special significance in the mechanism of aging and the regulation of "internal environment" of the body. The neurosecretory ability of hypothalamic nucleus changes with age, especially when the ability of pituitary-adrenal cortex system of hypothalamus to regulate internal and external environment decreases, which will lead to the imbalance of internal and external environment and affect life expectancy.