Effervescent tablet principle
Effervescent tablets use effervescent disintegrants produced by the reaction of basic carbonic acid and citric acid. When it is put into water, it will produce effervescent reaction, which will produce carbon dioxide vapor, thus producing a large number of bubbles in water. It is this phenomenon that gives the name effervescent tablets.
Brief introduction of effervescent tablets
Effervescent tablet is a relatively new pharmaceutical dosage form in China, which consists of main drug, diluent, adhesive, disintegrant, lubricant and other auxiliary materials. The diluent, adhesive, lubricant and other auxiliary materials used are the same as ordinary tablets, while the disintegrant is mainly acid source and alkali source. The commonly used acid sources are citric acid, malic acid, boric acid, tartaric acid, fumaric acid, inorganic acid (hydrochloric acid) and so on. Commonly used alkali sources are sodium bicarbonate, sodium carbonate and their mixtures.
At present, there are mainly two kinds of effervescent tablets on the market: external use and oral use. The oral use method is to take half a cup of cold water or warm water, put a dose of effervescent tablets into the cup, and drink it directly after the bubbles disappear completely.