The efficacy, function and taboo of angelica pubescens. Radix Angelicae Pubescentis is the name of a traditional Chinese medicine, which is the dried root of Angelica sinensis in Umbelliferae. The name of solo is very strange. Let's take a look at the efficacy, functions, taboos and related contents of solo activities.
Efficacy and Function of Radix Angelicae Pubescentis and Taboo 1 Efficacy and Function of Radix Angelicae Pubescentis
1, which can treat lumbago and leg pain, that is, pain caused by cold or moisture invasion.
2. It has a good therapeutic effect on itching and edema.
3, can be made into porridge, or soaked into tea has a good health care effect.
4, it has a certain effect on cold and bone joint pain, expelling wind and removing dampness.
5, can also be used for general pain.
taboo
It is not recommended for patients with yin deficiency, and patients with blood mania should use it with caution.
The efficacy and taboo of living alone II. The effect of living alone:
The taste is pungent, bitter and slightly warm.
(1) Expelling wind, eliminating dampness and relieving pain: treating rheumatic joint pain, waist and knee pain, headache due to yin cold and facial paralysis.
② relieving exterior syndrome and dispelling cold: treating wind-cold, aversion to cold and head and body pain. External use to treat sore and carbuncle swelling and pain. Oral administration: decoction, 3-10g; Or soak in wine; I still took the pills and dispersed them. External use: appropriate amount, decocted in water and washed.
The role of living alone:
1, sedative, hypnotic, analgesic and anti-inflammatory effects:
Oral injection of Radix Angelicae Pubescentis decoction or fluid extract (unknown variety) to rats or mice can produce sedative and hypnotic effects, and even prevent strychnine from convulsing frogs, but it cannot kill its rabbits. It is proved by hot plate method in mice that Duhuo Jisheng decoction has sedative, hypnotic and analgesic effects, and has anti-inflammatory effect on formaldehyde arthritis in rats.
2, the heart, vascular system:
Intravenous injection of crude Radix Angelicae Pubescentis (unknown species) into anesthetized dogs or cats can lower blood pressure, but it is not lasting. Tincture is more effective than decoction. Cutting vagus nerve did not affect its hypotensive effect, but after atropine injection, the hypotensive effect was partially or completely inhibited. It has inhibitory effect on isolated frog heart. When the frog leg is perfused, the decoction can constrict the blood vessels.
3, spasmolysis:
Bergamot lactone, xanthotoxin, saxifragin, isopsoralen B, etc. It has obvious spasmolytic effect on rabbit ileum. In the experiment of duodenum segment in rats, isoamycin, saxifragin, angelica dahurica, etc. It can obviously resist intestinal spasm caused by barium oxide.
4, antibacterial:
Radix Angelicae Dahuricae decoction has inhibitory effects on Escherichia coli, Shigella dysenteriae, typhoid Bacillus, Pseudomonas aeruginosa, Vibrio cholerae and human tuberculosis. The MTC of Duhuo Decoction against Mycobacterium tuberculosis in vitro is 1: 1000. Pine lactone has obvious inhibitory effect on Brucella, and its MIC is 1: 2500.
5, light sensitivity:
Radix Angelicae Pubescentis can cause solar dermatitis because it contains psoralen derivatives, such as bergamot lactone, xanthotoxin and imperatorin. Oral angelica pubescens can cause solar dermatitis. Photosensitive activity can be used to treat vitiligo. Photosensitive active substances, such as psoralen and flavin, can be used to treat vitiligo patients with increased skin pigmentation. The RNA content of DNA garbage increased. However, the toxic phenol, isoflavones and so on in Zanthoxylum bungeanum. No "allergic" effect.
6. Anti-ulcer
Furan coumarin compounds have anti-gastric ulcer effect. Experiments in rats show that bergamot and saxifragin have moderate protective effects on experimental gastric ulcer, while isoamycin and xanthotoxin have weak effects.
7. Anti-tumor:
It has a certain inhibitory effect. However, it is ineffective. Zanthoxylum bungeanum venom and bergamot lactone can kill Ehrlich ascites cancer cells.
8. Toxicity:
Toxin 400 mg/dl kills guinea pigs. Adrenal hemorrhage: 200-300 mg/kg can cause liver turbidity, steatosis and acute hemorrhagic necrosis, and in severe cases, renal congestion and hematuria. L-2 mg/kg caused liver necrosis in young rats for 5 months. A small amount of Angelica dahurica has an exciting effect on vasomotor center, respiratory center, vagus nerve and spinal cord, respiratory center, vagus nerve and spinal cord of animals, which can cause blood pressure to rise, pulse to become faster, breathing to deepen, salivation and vomiting. And a large number can cause compulsive intermittent spasm, and then general paralysis.
Taboo of living alone:
Use with caution for people with yin deficiency and blood dryness.
Prescription selection of Radix Angelicae Pubescentis:
1. Treatment of shaoyin headache: Radix Angelicae Pubescentis, Asari, Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Radix Rehmanniae, Notopterygii Rhizoma, Radix Saposhnikoviae and Glycyrrhrizae Radix, decocted in water. (Duhuo Asarum Decoction for Treating Symptoms and Pulse)
2. Treatment of wind arthralgia: Radix Angelicae Pubescentis, Heather, Radix Saposhnikoviae, Radix Aconiti Lateralis, Radix Aconiti, Herba Tianxiong and Herba Artemisiae Scopariae. Take two buckets of wine, soak for seven days, and take half a dose for three days, depending on knowledge. (Duhuo wine, a prescription that is eager to prepare a thousand daughters)
3. Treatment of lumbago due to cold-dampness and yin deficiency: Radix Angelicae Pubescentis, Rhizoma Atractylodis, Radix Saposhnikoviae, Asari, Rhizoma Chuanxiong and Radix Glycyrrhizae are decocted in water. (Duhuo Atractylodes Decoction for Vasculitis)
4, cure postpartum stroke, spasm, mouth can not be opened, cure blood gas pain, strain: live alone one catty, five liters of soybeans, three liters of wine a barrel. The first three flavors, living alone with wine stains before living. If you are in a hurry, cook it on low heat, reduce it by three liters, and remove me. Don't cook the soybeans too burnt, so that the smoke will come out. Make it with Duhuo wine.
5. Treatment of toothache: Radix Rehmanniae and Radix Angelicae Pubescentis each have three or two. The first two flavors are finely cut, and one liter of wine is soaked overnight, including it. ("a thousand women in a hurry")
Efficacy and taboo of Radix Angelicae Pubescentis 3. Efficacy and function of Radix Angelicae Pubescentis
Taste: pungent, bitter, slightly warm. Return to kidney and bladder meridian.
Indications: expelling wind and removing dampness, removing arthralgia and relieving pain. This product is bitter, fragrant and warm, good at expelling wind and removing dampness, dredging collaterals and stopping arthralgia. Cold-dampness arthralgia can be used for a long time. Because it enters the kidney meridian, it is good in nature and "specializes in treating lower jiao rheumatism" (herbal medicine), so it is most suitable for treating wind-cold-dampness arthralgia below the waist and knee. It also enters the bladder meridian, which is a "medicine for relieving the pathogenic wind-cold and dampness on the muscle surface" (note on materia medica), and is suitable for the exterior syndrome of exogenous wind-cold mixed with dampness.
1, treatment of arthralgia syndrome-lower body arthralgia syndrome, especially suitable for patients with pain in waist, knees, legs and feet belonging to cold and dampness.
This product is bitter, fragrant and warm, good at expelling wind and removing dampness, dredging collaterals and stopping arthralgia. Wind-cold-dampness arthralgia can be used regardless of age. Because it enters the kidney meridian, it is good in nature and "specializes in treating lower jiao rheumatism" (herbal syndrome). Therefore, it is especially suitable for treating arthralgia of the lower body, which is manifested as pain of waist, knees, legs and feet caused by cold and dampness. It is often combined with Taxilli, Saposhnikovia divaricata and Angelica sinensis, such as Duhuo Jisheng Decoction (Qian Jin Fang Yao).
2. Exterior syndrome of wind-cold-dampness-aversion to cold and fever, severe headache and general pain.
This product can dispel hard work, dry dampness, warm wind and cold, and enter the bladder meridian of Taiyang. It is a medicine for relieving muscles and exterior wind, cold and dampness (Notes on Materia Medica). Its efficacy is similar to that of Notopterygium, but its intensity is slightly weaker. It is suitable for exogenous wind-cold-dampness exterior syndrome. For those with aversion to cold, fever, severe headache and fatigue, it is often combined with Notopterygium Rhizoma, Ligusticum and Saposhnikovia divaricata.
In addition, this product can dispel wind, relieve pain and relieve itching, and can be used for shaoyin headache and skin itching.
Compatibility and application of radix Angelicae pubescentis
Radix Angelicae Pubescentis with Herba Taxilli: Radix Angelicae Pubescentis can search for wind, remove dampness and arthralgia, especially in removing kidney meridian and latent wind; Herba Taxilli has the effects of expelling wind and removing dampness, nourishing liver and kidney, strengthening tendons and bones, nourishing blood and moistening skin, expelling wind and removing dampness, dredging arthralgia and relieving pain, and it is classified as kidney meridian for nourishing kidney and strengthening tendons. It is suitable for symptoms such as soreness of waist and knees, unfavorable flexion and extension of joints, numbness of feet and difficulty in walking caused by liver and kidney deficiency or rheumatism.
Radix Angelicae Pubescentis with Asari: Radix Angelicae Pubescentis can eliminate dampness of kidney meridian, dredge collaterals and relieve pain; Asari dispels kidney meridian of cold. The combination of the two drugs has the effects of expelling wind, dispelling cold, removing dampness, dredging arthralgia and relieving pain, and is suitable for headache caused by exogenous wind-cold and stagnation of yin-qi, especially when encountering wind. Wind-cold-dampness arthralgia, lumbago, strong spinal cold, and joint pain of lower limbs.
Radix Angelicae Pubescentis: Radix Angelicae Pubescentis has fragrance, can dispel wind and overcome dampness, dredge collaterals and relieve pain; Wind, evacuation, good appearance, wind and dehumidification. Living alone is good at overcoming dampness, preventing wind and dispelling wind. The two drugs must be used together, and are suitable for headache, lumbago and joint pain caused by pathogenic wind, cold and dampness.
Radix Angelicae Pubescentis and Rhizoma Atractylodis: Both herbs have the functions of expelling wind, eliminating dampness and removing arthralgia, and Radix Angelicae Pubescentis is good at eliminating dampness and stopping arthralgia; Atractylodes lancea is good at eliminating dampness and turbidity, and drying spleen and eliminating dampness. The combination of the two drugs has the functions of sweating, expelling wind, removing dampness and relieving pain. Suitable for wind, cold and dampness.
Pharmacological effects of radix Angelicae pubescentis
This product has anti-inflammatory, analgesic, antiarrhythmic and antitumor effects.
1, anti-inflammatory and analgesic effects
The extract of Radix Angelicae Pubescentis can inhibit adjuvant arthritis, foot swelling and cotton granuloma caused by carrageenan and egg white in a dose-dependent manner. Oral administration of Radix Angelicae Pubescentis 1.5g/kg can alleviate arthritis induced by rubber plateau in rats. The volatile oil of Radix Angelicae Pubescentis can inhibit the ear swelling induced by croton oil in mice, and the median inhibitory dose (IDn) is 80 mg/kg and 89mg/kg. The anti-inflammatory effect of volatile oil from Radix Angelicae Pubescentis lasted for 4 hours in the experiment of foot swelling in rats.
2, the role of the cardiovascular system
The water extract of Radix Angelicae Pubescentis (26g/kg) can antagonize aconite alkaline arrhythmia in rats or mice by oral administration or intravenous injection of 2.6g/kg. Intravenous injection of water extract of Radix Angelicae Pubescentis can reduce the mortality of ventricular fibrillation and ventricular arrest induced by calcium chloride in mice, reduce the number of ectopic rhythms in the rat inner chamber within 30 minutes after coronary artery ligation, and prevent the occurrence of ventricular fibrillation in mice. Gamma-aminobutyric acid (GABA) is the active component isolated from water extract and acting on the heart. Parsley phenol methyl ether isolated from Radix Angelicae Pubescentis has the effect of relaxing thoracic aorta.
3, the role of the blood system
The ethanol extract of Radix Angelicae Pubescentis can inhibit ADP-induced platelet aggregation in rats in vitro, reduce the wet weight of arteriovenous bypass thrombosis in rats, delay the formation time of thrombosis in rats in vitro, shorten the length and wet weight of thrombus, and prolong the tail bleeding time of mice. Coumarin contained in Radix Angelicae Pubescentis can inhibit platelet aggregation and thrombosis, and dichloromethane extract of Radix Angelicae Pubescentis can inhibit the activities of finger lipoxygenase and cyclooxygenase in vitro.
The taboo of using solo work
Use with caution for people with yin deficiency and blood dryness.
Deficiency of qi and blood with pain and weakness of lower limbs due to yin deficiency are contraindicated. Taboo of syndrome of deficiency wind moving inside.
Use with caution for pregnant women and children.
It is not suitable for overdose or long-term use.
A few patients may have nausea, vomiting, stomach discomfort, or palpitation, palpitation, chest tightness and arrhythmia after taking the medicine. Large doses of drugs can cause dizziness, headache, numbness of the tongue and restlessness. In severe cases, hallucinations, delirium, mydriasis, knee hyperreflexia, generalized tonic spasm, convulsion, coma, general paralysis and even death may occur.