It is best not to use it often, because there are individual differences, and some people will feel uncomfortable after taking motilium, and even affect their endocrine.

Domperidone, also known as domperidone, is a new generation of gastric motility drug, which can directly act on the gastrointestinal wall, enhance gastric peristalsis, coordinate the movement of stomach and duodenum, thus inhibiting nausea and vomiting, and has a good effect on flatulence and dyspepsia. However, motilium can inhibit the central dopamine receptor, which reduces the amount of factors released from hypothalamus to the anterior pituitary gland, and the gonadotropin and adrenocorticotropic hormone secreted by the anterior pituitary gland will also decrease accordingly. Therefore, after taking motilium, some people will have delayed menstruation or even menopause because the secretion of ovarian hormones is affected.

At the same time, motilium can also increase the secretion of PRL, block the function of dopamine in the brain, make the acetylcholine system in a state of hyperactivity, and cause female lactation, feminine development of male breasts, asthma attack, extrapyramidal reaction, hematochezia, fecal incontinence and so on. The above adverse reactions caused by motilium often disappear after stopping using motilium.