1, immune response
Many rheumatism are immune diseases, so the immune response of the body can easily lead to this kind of rheumatism. When the exogenous or endogenous antigen substance of the body is stimulated to activate the corresponding T cells, if the T cells produce a large number of cytokines that can cause inflammation and damage or destroy human tissues or organs; Or T cells activate B cells to produce a large number of antibodies, which form immune complexes directly or after binding with antigens, thus damaging or destroying tissues and organs and eventually leading to rheumatic diseases.
2. hereditary
When connective tissue is invaded, it is also easy to cause rheumatism. But connective tissue-related diseases are hereditary, so some rheumatism is hereditary, especially human leukocyte antigen.
3. Infection factors
The external antigen and internal antigen are mentioned in the immune response, and some infectious factors, or antigens and superantigens produced by microorganisms, are easy to stimulate or aggravate this own immune response, thus leading to rheumatism or aggravating rheumatism symptoms.
4. Other factors
Rheumatism is caused by cold, fatigue, environment, physics and other factors, and they are also easy to induce or aggravate this immune response. If you want to know the cause, you still need to go to the hospital for examination. In addition, whether it is rheumatic patients or non-rheumatic patients, we must pay attention to proper warmth at ordinary times to avoid aggravating rheumatism or forming rheumatism.