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Can patients with dyslipidemia and high cholesterol take statins?
This is a rumor.

Raymond Francis, an expert in health education, has published many best-selling books and shared his health-preserving ideas at many medical conferences.

Raymond Francis specially recorded a video, which made an all-round "legitimate" attack on commonly used lipid-lowering drugs statins. He said in the video that although statins can lower cholesterol, they can't prevent heart attacks, and patients taking statins are more prone to heart failure, which leads to life-threatening.

Rumors:

There are many kinds of drugs to reduce blood fat. Statins are strongly recommended, because statins not only have obvious lipid-lowering effect, but also have fewer side effects, and the incidence of cardiovascular events in patients after application is also significantly reduced.

Statins can not only reduce blood lipid, but also prevent cardiovascular diseases. For more than a century, medical scientists have done countless animal experiments and epidemiological investigations, confirming that serum cholesterol level is closely related to coronary heart disease mortality: the higher the serum cholesterol level, the higher the coronary heart disease mortality rate. Since the advent of statins for 40 years, a large number of clinical trials and practices have confirmed that the application of statins has greatly reduced the level of bad cholesterol and brought about a significant reduction in cardiovascular and cerebrovascular events.

Nowadays, we can say without reservation: there is no atherosclerosis without cholesterol! Low density lipoprotein cholesterol (LDL-C) is the chief culprit of coronary heart disease! Lowering LDL cholesterol will inevitably reduce the incidence of cardiovascular diseases!

Statins are not only lipid-lowering drugs, but also recognized anti-atherosclerosis drugs, which have been identified by various guidelines as one of the most important first-line drugs for primary and secondary prevention of cardiovascular and cerebrovascular diseases.

Objectively speaking, no drug is perfect, and there will be some side effects, and statins are no exception. Statins do have potential "muscle toxicity" side effects in application, and rhabdomyolysis may occur in severe cases. However, it should be noted that such side effects are very few.

Can statins hurt the liver if taken for a long time? Perhaps the probability is extremely low. The association between statins and the risk of new-onset diabetes is mainly concentrated in people with high-dose statins and abnormal glucose tolerance, but the effect of long-term application on reducing cardiovascular and cerebrovascular diseases is much higher than that of new-onset diabetes. Statins can not only aggravate renal failure, but also maintain renal function to some extent. There is no evidence that statins increase the risk of cancer. At present, there are many clinical studies on the effect of statins on the prognosis of patients with heart failure. Although the positive result of "statins are obviously beneficial to the recovery of heart failure" is not universally obtained, it will certainly not aggravate heart failure.

Drugs are not ordinary foods, and their benefits and risks should be fully weighed before use. It is obviously unwise to completely deny their positive role because of a little defect! Just like picking up sesame seeds (avoiding the possible side effects of low incidence) and losing watermelon (obviously reducing cardiovascular and cerebrovascular events).

Expert: Wang Fang, Deputy Director of Cardiology Department of Beijing Hospital.

Evaluation expert: Ma Manling, director of therapeutic drug monitoring in the Pharmacy Department of the First Affiliated Hospital of Harbin Medical University, and member of the Scientific Communication Committee of Chinese Pharmaceutical Society.

Producer: Cop China-Scientific Refutation