Onychomycosis is caused by fungal infection and is also one of the common skin diseases. Our hospital adopts osmotic softening therapy to accurately treat stubborn onychomycosis such as nail deformation, thickening, whitening, blackening and yellowing caused by various fungal infections. Through Waldmann UV80 1 microwave radiation combined with drug iontophoresis, it can quickly penetrate into the root of diseased nails, kill pathogenic bacteria, promote nail bed maintenance, repair nail regeneration and cut off transmission.