2. To sum up, "Liu Bei Keanu" is the name of traditional Chinese medicine, which comes from Common Herbs in Zhejiang and is an alias of "Lingyinchen" recorded in Records of Traditional Chinese Medicine [1]. Pharmacopoeia of People's Republic of China (PRC) (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
3. Beiliu's minions are nicknamed Yinchen, Yinchen, Yinchen and Yuanxiang [2].
Source and place of origin: the whole grass of Scrophulariaceae plant Artemisia capillaris. [2]. Location: Jiangsu, Anhui, Zhejiang, Yunnan and Guangxi [2].
5 tastes bitter and cold [2].
6 Functions are mainly used for clearing heat and promoting diuresis, promoting blood circulation and removing blood stasis [2].
1. Treat jaundice hepatitis, cholecystitis, bean disease, urinary calculi, dysuria, edema, abdominal distension, bloody dysentery, bloody stranguria, postpartum abdominal pain and traumatic injury pain [2]. Decocting: 9 ~ 15g [2].
2. Treat traumatic bleeding, burns and scalds [2]. Grinding or flattening [2]
7 Pay attention to pregnant women and avoid taking [2].
8 chemical composition this product contains apigenin, luteolin, etc. , cardiac glycoside and volatile oil [2]. The volatile oil contains α limonene, 1, 8 cineole, menthone and so on [2]. The aboveground part contains linalool, isoctheanine, ryegrass lactone and so on [2].
9 Pharmacological Action This product has the functions of dilating bile duct, promoting bile excretion and liver cell regeneration; It has protective effect on experimental liver injury [2]. It can inhibit typhoid dysentery and Escherichia coli [2].
10 Pharmacopoeia standard Beiliu Keanu 10. 1 was named Beiliu Keanu.
Beiliujinu
capillary artemisia
10.2 Source: This product is the dried whole grass of Heibei Jinu. Scrophulariaceae Harvest in autumn, remove impurities and dry in the sun.
10.3 features: this product is 30 ~ 80 cm long, all of which are short hairs. The roots are short and curved, slightly branched. The stems are cylindrical and angular, some have branches on the upper part, and the surface is brown or dark brown; Fragile, easily broken, yellow-white in cross section, hollow or with white pith. The leaves are opposite, mostly falling off and broken, and the whole leaves are deep pinnate dark green. The raceme is terminal, with short stalks, long tubular calyx, yellow-brown to dark brown, longitudinal edge 10, 5-lobed apex, brown corolla, and often falling off. Capsule narrowly ovoid-elliptic, slightly shorter than calyx, brownish black. The seeds are very small. A slight breath, a faint taste.
10.4 identification (1) Cross section of the stem of this product: non-glandular hairs can be seen on the epidermis, with 2-4 cells of non-glandular hairs. The cortex consists of 2 ~ 4 rows of cells. The outer sheath fibers are annular. The phloem is very narrow. The cambium is not obvious. Wood 10 has multiple rows, which are composed of ducts and wood fibers, and the ray cells are in a single row. The medullary parenchyma cells are closely arranged, and some cells have pits.
(2) Take 2g of this product powder, add 20ml of methanol, perform ultrasonic treatment for 30min, filter, and concentrate the filtrate to 1ml as the test solution. Another luteolin reference substance was added with methanol to prepare a solution containing 1 ml as the reference substance solution. According to the thin-layer chromatography test (Appendix ⅵ b), absorb 5ul of each of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, develop with toluene-ethyl formate (5: 4: 1) as the developing agent, take them out, dry them, and spray 1% aluminum trichloride test solution at105. In the chromatogram of the test sample, fluorescent spots with the same color appear in the position corresponding to the chromatogram of the control sample.
The water content of 10.51shall not exceed 12.0% (appendix ⅸ H first method).
10.5.2 the total ash content shall not exceed 8.0% (appendix ⅸ k).
10.6 extract shall be determined by the hot soaking method under the alcohol-soluble extract determination method (appendix X A), with 70% ethanol as the solvent, which shall not be less than 10.0%.
The content of 10.7 was determined by HPLC (Appendix VI D).
10.7. 1 chromatographic conditions and system applicability test: octadecylsilane bonded silica gel is used as filler; Using acetonitrile 0.3% phosphoric acid solution (30∶70) as mobile phase; The detection wavelength is 349 nm. According to the luteolin peak, the theoretical plate number should not be less than 8000.
10.7.2 preparation of reference substance solution: take an appropriate amount of luteolin reference substance, weigh it accurately, and add methanol to make a solution containing 25μg per 1ml.
10.7.3 preparation of test solution take about 1g of this product powder (pass through No.2 sieve), weigh it accurately, put it in a conical flask with a stopper, add 25ml of methanol accurately, plug it, weigh it, perform ultrasonic treatment (power 250W, frequency 40 khz) for 30 minutes, let it cool, weigh it again, and.
10.7.4 determination method Accurately suck the control solution and the test solution 10μl respectively, inject them into the liquid chromatograph, and determine to obtain the product.
The content of luteolin (C 15H 1006) in this product shall not be less than 0.050% based on the dry product.
10.8 Beiliu decoction pieces 10.8. 1 Processing to remove impurities, cleaning, cutting into sections and drying.
10.8.2: Bitter taste and cold. Into the spleen, stomach, liver and gallbladder.
10.8.3 Functions and indications: promoting blood circulation, removing blood stasis, dredging channels and relieving pain, cooling blood to stop bleeding, clearing heat and promoting diuresis. Can be used for traumatic injury, traumatic hemorrhage, blood stasis amenorrhea, menoxenia, postpartum stasis pain, scar accumulation, bloody dysentery, bloody stranguria, damp-heat jaundice, edema, abdominal distension, and leukorrhagia.
10.8.4 Usage and dosage 6 ~ 9g.
10.8.5 Store in a dry place.
10.9 source