This is also the question that scientists have been asking. Most people think that obesity is a chronic metabolic disease caused by many factors, which leads to excessive accumulation and/or abnormal distribution of fat in the body and harms health.

In fact, obesity is often caused by heredity, inactivity and excessive energy intake. From the perspective of metabolic research, it is based on metabolic disorder, which is the central link of obesity from gene to clinical manifestation.

Obese people often have disorder of fat metabolism and excessive fat synthesis, but there is no obvious abnormality in fat hydrolysis and fat decomposition and oxidation. Plasma triglycerides, free fatty acids and cholesterol are generally higher than normal levels. When using low-energy diet to treat obesity, the tendency of plasma ketone body increase or ketonemia is often lower than that of normal people.

With the rapid progress of genomics research, it has been found that the differences of gene polymorphism make people of all ages more likely to be obese. Under the above background, combined with the adaptive changes of intestinal flora structure after the change of dietary structure, these people with genetic susceptibility have significantly different responses to the three macro nutrients (carbohydrate, protein and fat), which leads to obesity.

Many people mistakenly think that obesity is overnutrition, but in fact it is just excess fat, and other nutrients may be insufficient, which leads to the lack of enzymes for fat metabolism and the decline of liver metabolism. Obesity is the heat that cannot be metabolized due to unbalanced nutrition and irregular diet, which is converted into fat and accumulated.

Never play this with fat people …

Obesity is a chronic metabolic disease. It is a phenomenon of organ function decline, especially the liver. Therefore, we eat too many calories to get fat, not too much nutrition to get fat.