Excessive fatigue will explode the liver, and moderate exercise should be beneficial. 220 minus your age is your maximum heart rate, the exercise heart rate should be controlled within 80% of the maximum heart rate, and the exercise time should not exceed one hour. I don't feel too tired after exercise, and I won't affect my sleep that day. I can recover from fatigue in a day or two. The changes of liver function and viral DNA were monitored regularly (every 3 to 6 months).