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What is the mechanism of rhabdomyolysis caused by exercise? What are the precautions?
Let me briefly introduce rhabdomyolysis, which refers to the decomposition of muscle fibers after skeletal muscle injury, resulting in a large number of cell contents such as potassium, phosphorus, myoglobin and creatine kinase leaking into the blood circulation. Skeletal muscle injury itself may lead to muscle pain and fatigue, and even more terrible complications can be life-threatening: early complications include hypocalcemia, liver injury, arrhythmia and even cardiac arrest caused by hyperkalemia, and late complications include blood coagulation, renal damage and even renal failure.

There are many possible reasons for this skeletal muscle injury, such as excessive drinking, excessive exercise, crush injury, heatstroke, drugs, poisons, diseases and so on. So I won't expand here, just say sports rhabdomyolysis.

A report from ACSM (American Sports Medicine Association) points out that sports rhabdomyolysis is very common among athletes. It is not only people who do not exercise for a long time who are prone to rhabdomyolysis. Although low physical fitness is a risk factor, high physical fitness exercisers who have been exercising for a long time may also have rhabdomyolysis, such as repeating unfamiliar movement training, such as overtraining. Many other factors may make exercise more likely to cause rhabdomyolysis, including dehydration, damp heat, statins, ephedrine, high-dose caffeine, alcohol and so on. There are also some people who are more prone to rhabdomyolysis than others in the same exercise environment, such as genetic problems such as changes in sickle cell traits, deficiency of phosphofructokinase and adenosine deaminase, as well as exercise pattern problems such as nerve control disorder and muscle imbalance. Of course, there may be other diseases. This high-risk group is not only more prone to rhabdomyolysis, but also more prone to relapse after recovery. For patients with recurrence, it is suggested to have a comprehensive physical examination and explore the potential influencing factors.

For the general sports crowd, the measures to prevent sports rhabdomyolysis are integrated into one sentence, that is, a healthy lifestyle: using scientific knowledge to comprehensively guide our lifestyles such as activities, work and rest, diet, physical examination and hygiene.

This sentence sounds simple, everyone thinks they understand it, but it does involve too many fields of scientific knowledge, and the actual situation is that almost everyone does not understand it. Of course, if you don't understand, you can also study. Unfortunately, according to my observation in the gym for many years, scientific knowledge is the most unpopular thing. Members don't like it, and neither does the coach.

You can see countless people who are eager for success, unable to settle down and learn even a little complicated health knowledge, and start all kinds of nonsense directly based on the simplest assumptions or hearsay-euphemistically called: just do it. As soon as I got up, I slammed the spinning bike and practiced interesting group lessons such as CROSSFIT. I copied the plan and practiced five differential and six differential. Coupled with various mistakes in action patterns, the risk of rhabdomyolysis cannot be greatly increased. There are many more wonderful things: those who don't eat dinner or breakfast, those who come to exercise without eating or eating casually, those who take a sauna before, during and after exercise, those who practice crazily in a special sweat-proof suit wrapped in plastic wrap on a hot day, and those who are strong in sports never drink water-I held a card exercise in Chengdu Legend Fitness Wangfujing Store a few years ago, and a coach came to educate me not to drink water during the exercise.