In terms of safety, there have been no serious adverse reactions since the product was launched. Some common adverse reactions, such as skin flushing and vaginal dryness, are usually mild or moderate, and patients are easy to tolerate. In terms of curative effect, this product has a remarkable feature that it takes a long time to take effect, and patients need to take it for a long time to achieve the effect.
Anastrozole is absorbed quickly, and its blood concentration is high, which usually occurs within 2 hours after taking the drug (on an empty stomach). Anastrozole clearance is slow and the plasma clearance half-life is 40- 50 hours. Food has a slight effect on the absorption rate, but it does not affect the absorption degree. When the tablet is taken once a day, the slight effect of food on the drug absorption rate will not affect the plasma steady-state concentration. After seven days, the plasma concentration can reach 90 ~ 95% of the steady-state concentration, and there is no evidence that the pharmacokinetic parameters of anastrozole are time or dose dependent.