1, thyroid hormone.
Thyroid hormone can promote energy consumption, so as to achieve the purpose of weight loss, but only in the case of large doses can there be obvious weight loss effect. Moreover, thyroxine can also damage the function of the heart, accelerate protein decomposition, and cause muscle lesions and osteomalacia. Therefore, the US Food and Drug Administration (FDA) has formally proposed that the label of thyroid drugs must be marked as "not used for weight loss treatment". However, in recent years, some scholars have re-evaluated the value of thyroid hormone in the treatment of obesity. It is suggested that obesity can be treated with low dose. At this time, the decomposition of protein in the body has not increased significantly, but it must be carried out under the guidance of a doctor. If you take it for a long time, it will lead to too much thyroid hormone and cause hyperthyroidism.
2. Dehydroepiandrosterone.
It is a sex hormone secreted by adrenal cortex. Excessive intake is harmful to human metabolism and can lead to infertility and amenorrhea.
3. Growth hormone.
It plays an important role in the development of human adipose tissue, especially for young people before the age of 20. Growth hormone deficiency in children and adults can lead to obesity, so growth hormone has a good effect in treating this kind of obesity. Some people use growth hormone to treat simple obesity, especially childhood obesity, but its effective weight loss dose is still inconclusive. The Australian research team found a growth hormone analogue called AOpo40 1, which on the one hand specifically promotes fat decomposition, on the other hand directly inhibits fat accumulation, thus achieving the effect of losing weight. This drug has no other effects of growth hormone, and animal experiments show that it has not found potential toxic and side effects, so it is an ideal weight loss drug so far.
4. Amphetamines and their analogues.
Include methamphetamine, benzyl methamphetamine, amfepramone, dextroamphetamine and phenylbutylamine, which can reduce appetite, reduce food intake and lose weight. This medicine has a definite weight loss effect. After taking it for 3 ~ 6 months, most patients can lose 4 ~ 8 kg. Its adverse reactions are mainly excessive excitement, such as irritability, insomnia, dizziness, headache, increased heart rate and blood pressure, and gastrointestinal side effects such as nausea, vomiting, diarrhea, increased sweating, euphoria and addiction. Among them, amphetamine is the earliest appetite suppressant, but its adverse reaction is great, and its curative effect is not better than some appetite suppressants developed at present. At present, the use of amphetamine as a food inhibitor has been banned in foreign countries, and the most commonly used drug of this kind is amphetamine.