Thrombocytopenic purpura is characterized by significant thrombocytopenia, accompanied by cutaneous mucosal purpura. In severe cases, bleeding may occur in other parts, such as nosebleeds, gingival exudation, menorrhagia or severe hematemesis, hemoptysis, hematochezia and hematuria. Intracranial hemorrhage is the fatal cause of this disease. Henoch-Schonlein purpura is characterized by scattered spots on the skin of limbs or spreading to the whole body. Severe cases are accompanied by joint pain or abdominal pain, bloody stool, vomiting blood, collapse and so on. In severe cases, it can develop into henoch-schonlein purpura nephritis. Thrombocytopenic purpura can be divided into primary and secondary. Primary thrombocytopenic purpura is an immune syndrome and a common hemorrhagic disease. It is characterized by the existence of anti-platelet antibodies in blood circulation, which makes platelets destroy too much and causes purpura; However, the megakaryocytes in bone marrow are normal or increased, which is childish. Clinically, it can be divided into acute and chronic, and its pathogenesis and manifestations are obviously different.
The acute type is mostly 10 children, both male and female. There is no difference between the sexes. Most of them occurred in winter and spring, and there was a history of virus infection before illness, mostly upper respiratory tract infection, rubella, measles and chickenpox. After vaccination, the incubation period of infection and purpura is mostly within 1~3 weeks. Adult acute type is rare, often related to drugs, and the condition is more serious than that of children. Have a sudden fever.
Mainly skin and mucous membrane bleeding, often more serious. Skin bleeding is petechiae with different sizes and uneven distribution, which mostly occurs in limbs. Mucosal bleeding includes nosebleed, gingival bleeding, oral and tongue mucosal blood bubbles. There are often gastrointestinal bleeding, urinary tract bleeding, subconjunctival bleeding and a few retinal bleeding. Common spinal cord or intracranial hemorrhage can cause paralysis of lower limbs or intracranial hypertension, which can be life-threatening.
Chronic type is more common, accounting for 80% of primary thrombocytopenic purpura, and most of them are 10~40 years old, and women are 3~4 times as many as men. Sneak when you are sick. Patients may have persistent bleeding or recurrent attacks, and some may show local bleeding tendency, such as recurrent epistaxis or menorrhagia. Congestion and ecchymosis can occur in any part of skin and mucosa, but more often in distal limbs. There may be gastrointestinal and urinary tract bleeding. Deep hematoma can also occur after trauma. Intracranial hemorrhage is rare, but it can still occur during acute attack. You can occasionally touch the spleen when inhaling deeply.
The etiology and pathogenesis of primary thrombocytopenic purpura have not yet been clarified. It is considered as an immune-related disease.
At present, the first choice for western medicine to treat thrombocytopenic purpura and allergic purpura is hormone. Platelets can generally increase after taking it, but the side effects of hormones are very great. While increasing platelets, it will also increase many new diseases, such as centripetal obesity, hypertension, diabetes, osteoporosis and so on. After reducing the dosage of hormone, platelets will drop again, and will still recur after stopping taking the drug. Splenectomy is dangerous and difficult for patients to accept. Spleen is the immune organ of human body. After splenectomy, the patient's immune function is low, which is easy to cause serious infection and bring great pain to the patient's body and mind. The recurrence rate after splenectomy is about 58%. Is there a method that can not only raise platelets, control the disease, but also replace hormones without side effects on the human body? The expert group led by Professor Lan, a national immunologist and founder of Yiguang Primary Thrombocytopenic Purpura in Beijing Gulou Hospital of Traditional Chinese Medicine, established a complete concept of TCM immunology for the first time on the basis of years of clinical experience and painstaking research. This achievement clarified the pathogenesis of thrombocytopenic purpura.
Professor Lan was born in 1965 in a family of traditional Chinese medicine of She nationality in Fujian, and graduated from Jiangxi College of Traditional Chinese Medicine. Engaged in the treatment and research of immune diseases for nearly 30 years. He is keen on medicine and diligent in his career. At present, he is an expert of Gulou Chinese Medicine Hospital affiliated to Capital Medical University. He is the director of Dalian Lupus Erythematosus Research Institute, the director of Weihai Shuangfeng Chinese Medicine Research Institute, the director of Chinese Medicine Association, the deputy director of AIDS Prevention and Control Branch of Chinese Medicine Association, the chairman of China International Health Promotion Association and the editorial board of Capital Medicine magazine.
Professor Lan believes that the pathogenesis of thrombocytopenic purpura starts from the bone marrow, and under the stimulation of the inducement (which can come from inside and outside), the "marrow" of qi-constant fu-organs reacts, resulting in a whole model of fu-organs to cope with the change. This pattern is projected to all organs of the whole body in a holistic way. It acts quickly and forms a new physical state. When this state further strengthens the stimulation of "bone marrow", a vicious circle is formed. The persistent effect of this vicious circle on the whole body causes pathological changes of the body, which can be manifested as systemic symptoms, skin ecchymosis or petechia, nosebleed, gingival bleeding, hematuria, menorrhagia, hematochezia and cerebral hemorrhage. , can also show the symptoms of anemia. Which is what we call thrombocytopenic purpura.
According to this principle, Yisui Yangxue Granule developed by Professor Lan has made great contributions to the treatment of thrombocytopenic purpura. The therapeutic principle of this medicine is to make marrow for "Qiheng Fu-organs", from which it spreads to all organs of the whole body, and at the same time repair the organ damage that has been caused, so that the disease begins to improve and a new human state is formed. Due to the diversity of organ damage, adjuvant drug therapy should be adjusted at any time on the basis of syndrome differentiation to achieve the best therapeutic effect. Statistical analysis of tens of thousands of patients who came for treatment showed that the total effective rate was 93.3% and the clinical cure rate was 36.6%.
Professor Lan and Director Sun Xiumei of Gulou Chinese Medicine Hospital affiliated to Capital Medical University have been engaged in the research and treatment of immune diseases for many years, which has given many desperate patients with thrombocytopenic purpura a new life.
Mr. Chen from Ganzi, Sichuan, has suffered from primary thrombocytopenic purpura for more than 9 years. He often has stomachache, anemia and skin purpura. I have been to many hospitals, checked antibodies, had bone spurs and suffered a lot, but I just can't make a diagnosis. He is sad every day and can't laugh. Later, he listened to a friend's introduction that the treatment of primary thrombocytopenic purpura in Beijing Gulou Hospital of Traditional Chinese Medicine was unique, and his friend's illness was cured there, but he still didn't believe it, so he wrote a letter seeking medical treatment with the mentality of giving it a try, which introduced his condition in detail and attached the examination results. I hope the experts can help. After receiving the letter, experts and professors in this department carefully read his illness introduction and related examination results, and found that his platelet value was only 6.5438+0.5 million, while the normal platelet value should be between 6.5438+0.3 million -0.3 million, which was initially diagnosed as thrombocytopenic purpura. Soon after, Mr. Chen received a reply and prescribed Yishui Yangxue Granules for him. After taking the medicine for more than 2 months, Mr. Chen found that his condition improved obviously, so he continued to write letters to explain the development of his condition and ordered the medicine by mail. From June 5438 to October 2004, he finally got on the train to Beijing and went to the hospital for personal treatment.
After several months of treatment, at present, Mr. Chen's condition has basically recovered, and his platelets have risen to 1.99 million, and other physical symptoms have disappeared. Mr. Chen regained his old smile.
Zhang Yu, 16 years old, a girl from Xianju County, Zhejiang Province, was diagnosed with primary thrombocytopenic purpura in 2002. She was treated in a local hospital, mainly using hormones. Her condition has been ups and downs. Parents are also in great pain when they see their lively and lovely daughter suffering from illness. They hoped to find a drug to replace hormones and cure their daughter's illness, so they asked people to ask around. Later, I heard that Yiguang's primary thrombocytopenic purpura specialist in Beijing Gulou Hospital of Traditional Chinese Medicine didn't need hormone treatment, so Mr. Zhang and his lover took time off to take their children to Beijing. In this specialty, the attending doctors, Professor Sun Xiumei and Professor Lan, treated carefully, and gradually reduced the dosage of hormones through Liang Xue Xiaoban Granule combined with traditional Chinese medicine, and finally completely replaced hormones. Now Zhang Yu's platelet count has risen to 1 16000, reaching the normal value.