If you want to accompany others (or play by yourself), then the prelude is played according to the first line, with the left hand bass score (below the first line) and the right hand treble score (above the first line).

Then the bottom is the same, the bottom line of the left hand and the middle line of the right hand.

If you want to play a melody,

The prelude is the same as above. And then at the beginning,

Play the first line with your right hand (the line with lyrics) and the last line with your left hand.