The slimming chip will interact with human vagus nerve, which is the key to forming appetite. It can not only check the calorie intake of food, but also control the chemical and electronic reactions in the body, which just affect the relationship between appetite and satiety. The microchip contains an "intelligent implantable mediator" with a width of only a few millimeters, which is connected to the sympathetic nerve in the peritoneal cavity through a cuff electrode. Sympathetic nerve mainly controls respiration, heart rate, acid secretion of digestive system and intestinal peristalsis, and is also responsible for feeding back the information of different systems in the body to the brain.

Microchips and skin electrodes can read and process electrical and chemical signals related to appetite in sympathetic nerves. Then, the microchip sends electrical signals to the brain in a way of "simulating nerve impulses", and the brain is responsible for controlling food intake, thus reducing or preventing the desire to eat, and making obese people more cautious and temperate when eating.

The researchers also added an intelligent program to this tiny chip, which can simulate the neural signals that control appetite. Monitoring these neural signals can eventually stimulate the brain to counter the monitored neural signals, thus controlling appetite, rather than preventing people from eating.