For example, Du Xing muscular dystrophy, also known as Duchenne muscular dystrophy, is a genetic disease. Patients with this disease develop in adolescence, mainly manifested as difficulty in turning over, sitting up and standing. The disease is a rare disease, and there is no treatment at present, and muscle atrophy will gradually increase until death.
neuropathy
Mainly refers to neurogenic muscular atrophy, such as amyotrophic lateral sclerosis, cerebral infarction, polio and so on. Neuropathy will cause nerve signal conduction disorder, which will lead to some useless muscle fibers, reduce exercise ability and lead to disuse muscular atrophy.
In addition, when neurons are injured, the acetylcholine released from their terminals decreases, and the neurotrophic effect is weakened, thus causing muscle atrophy.
wound
When a fracture occurs, it may lead to muscle atrophy in the affected area. On the one hand, in the process of fracture treatment, due to the long-term fixation of the affected limb, the activity of the limb decreases, resulting in disuse muscle atrophy. On the other hand, fractures may also damage the surrounding nerves or cause compression of the spinal cord and nerves, and muscle atrophy may occur in this innervated area.
Other diseases
Such as cervical spondylosis, lumbar disc herniation and tumor. , can cause the corresponding parts of the spinal cord and nerve compression, which may cause muscle atrophy;
Anorexia, malnutrition, Cushing syndrome, hyperthyroidism, etc. It can also lead to muscle atrophy;
Inflammatory diseases, such as myositis and arthritis, and chronic infections can also lead to muscle atrophy.