Because it is a metabolic disorder, if diet control is ineffective, it must be controlled with drugs for a long time. Commonly used drugs are: the mechanism of probenecid uric acid excretion agent is to inhibit the reabsorption of uric acid by renal tubules, increase the excretion of uric acid from urine, thus reducing the concentration of uric acid in blood, and finally reducing the deposition of urate in soft tissues and the occurrence of gouty inflammation. The following patients should not be used; Uric acid caused by urinary calculi, blood erosion, chemotherapy and cancer. Benzbromarone is a derivative of benzofuran, which can inhibit the reabsorption of uric acid by renal tubules, thus reducing the concentration of uric acid in blood. It is easy to be absorbed orally and its metabolites are effective. The uric acid in the blood 24 hours after taking the medicine was 66.5% of that before taking the medicine. This product can be taken together with acetylsalicylic acid, other salicylic acid preparations and bizinamide, which can weaken the effect of this product. This product. Adverse reactions can lead to neutropenia, so check the blood picture regularly.
2. Commonly used anti-inflammatory drugs
Acute gout can be treated with diclofenac sodium, also known as 2 grams of diclofenac sodium, a non-steroidal anti-inflammatory analgesic, 25mg, one or two tablets each time, two or three meals a day. Patients with gastropathy should take it according to the doctor's advice. Celebrex (Celecoxib) 200mg, once or twice a day, after meals, one capsule each time. Patients with heart disease and stomach disease must follow the doctor's advice.
3. Traditional Chinese medicine for inhibiting uric acid synthesis
Pueraria lobata, Lophatherum gracile, Gynostemma pentaphyllum, Ligustrum lucidum and Cordyceps sinensis all have the effect of reducing uric acid.
4. Supplement
In kidney metabolism, more than 90% is converted into 3- methyl-histamine, which can excrete uric acid.