Ulcerative colitis is a chronic nonspecific inflammatory disease of colon and rectum with unknown etiology, and its lesions are limited to the mucosa and submucosa of large intestine. The lesions are mostly located in S-shaped colon and rectum, and can also spread to descending colon or even the whole colon. The course of disease is long, and it often recurs. The disease can occur at any age, but it is most common in 20 ~ 30 years old. Symptoms include bloody diarrhea, abdominal pain, bloody stool, weight loss and acute diarrhea.

There is no best treatment for ulcerative colitis. At present, no method is suitable for all patients with ulcerative colitis. Because everyone's etiology and severity of the disease are different, the final treatment should be decided according to the examination results. Generally speaking, the treatment of ulcerative colitis includes general treatment and drug treatment.

First, general treatment. During the activity, you should stay in bed and eat a diet with high nutrition and low residue. Severe cases need temporary fasting. According to the doctor's advice, rehydrate and correct the disorder of water, electrolyte and acid-base balance. Choose a reasonable nutrition model according to the doctor's advice. If there are diseases such as intestinal obstruction and short bowel syndrome, parenteral nutrition is needed. Can vitamin B be supplemented when anemia occurs? , folic acid, blood transfusion treatment can be carried out according to the doctor's advice when necessary. Hypoalbuminemia can be infused with albumin or plasma according to the doctor's advice.

Second, medication. The representative drugs of aminosalicylic acid preparation are sulfasalazine and 5-aminosalicylic acid, which are suitable for people in mild to moderate active stage and can also be used for postoperative maintenance treatment. Commonly used drugs include mesalazine, Oshara Qin and balsalazide. People with liver dysfunction, elderly patients, pregnant women and lactating women should use this medicine with caution.

Glucocorticoid is one of the effective drugs to control disease activity, which is suitable for the active period of disease. Aminosalicylic acid preparation or immunosuppressant can be added. Representative drugs include budesonide and prednisone. Have a serious history of mental illness; Active gastric and duodenal ulcer or recent gastrointestinal anastomosis; This drug is prohibited for patients with osteoporosis, diabetes, severe hypertension, glaucoma and cataract.

The cause of ulcerative colitis is still unclear, but related research shows that it is probably because diet is related to genes, so we must correct our eating habits, quit smoking and drinking, and so on.