During the epidemic in novel coronavirus, it is very important to do personal protection to avoid virus infection. The main measures include the following: First, minimize going out, don't go to crowded places, and avoid close contact with anyone with cold or flu-like symptoms. Second, when going out to public places, seeking medical treatment or taking transportation, pay attention to wearing medical surgical masks or N95 masks. Three, don't contact, buy and eat wild animals, avoid contact with unprotected wild animals, poultry and livestock. Fourth, pay attention to hand hygiene, wash your hands frequently, use hand sanitizer or soap, tap water to suck your hands or use alcohol-containing antibacterial hand sanitizer. Don't cover your hands when sneezing or coughing. Cover your mouth and nose with elbow or tissue. Six, keep the bedroom and workplace clean, often open the window, keep ventilated. Seven, pay attention to drink more water, rest more, avoid staying up late, moderate exercise, in order to improve individual immunity, pay attention to nutrition, reasonable diet, meat, poultry, eggs should be fully cooked before eating. At present, there are no effective antiviral drugs in novel coronavirus, and the main clinical treatments are isolation treatment and symptomatic support treatment.