Wan Mizhai's academic contribution is to establish the theory that "three are greater than one and four are less than one".

On the basis of summarizing predecessors' experience and long-term clinical practice, Wan Mizhai further improved the theory of children's physiology and pathology, and put forward the theory of "three excess and four deficiency", that is, "the liver is always excess, the heart is always excess, the yang is always excess, the spleen is often insufficient, the lung is often insufficient, the kidney is often insufficient, and the yin is often insufficient". For example, in Pediatrics, it is said that "the liver is often surplus and the spleen is often insufficient, which is a dirty qi. Covering the liver is the qi of xiaoyang, and having children like mu is the qi of xiaoyang's growth, so it is surplus. The stomach is crisp and thin, the grain is not full, and this spleen is insufficient. " The so-called excess and deficiency does not refer to the general excess and deficiency, nor is it the pathological state of "excess of evil and deficiency of essence", but first demonstrates the physiological characteristics of children and further demonstrates the pathological characteristics of children. For example, "the liver is always flourishing" refers to the rapid growth and development of children in physiology, such as the germination of plants and trees, which is full of vitality, benefiting from the exuberance of the liver governing hair growth; Pathological features refer to the fact that children easily turn heat into fire after feeling evil, which leads to liver wind. Wan Mizhai's "spleen deficiency" refers to children's rapid growth and development, and the demand for subtle substances is more urgent than that of adults, but the function of spleen in controlling transport is not perfect. In order to meet the growing needs, the spleen and stomach must constantly improve their ability to transport and transform fine substances; Pathologically, it refers to children's improper diet and imbalance of cold and temperature, which is easy to cause imbalance of spleen and stomach transport and transformation, leading to spleen and stomach diseases. Wan Mizhai's theory of "excess of deficiency" further enriches the pathological characteristics of children's "deficiency is easy to be solid, and cold is easy to be hot", which provides a systematic theoretical basis for guiding pediatric clinical treatment.

First visit, fourth visit and reference.

Wan Mizhai attaches great importance to free clinic. Because pediatrics is also called "dumb department", babies can't talk, but people who can talk may not be trusted. In addition, frequent crying makes diagnosis difficult, so it is particularly important to see a doctor.

Wan Mizhai pointed out in Pian Yu's Heart Book: "When we look at children's diseases, we should look at them first and then feel the pulse." . "The Secret of Baby Care" also said: "Children look at their appearance when they are sick, young people are responsible for fright, red is responsible for fever, and yellow is responsible for malnutrition ... The spleen, lips, heart and tongue are connected in liver disease, and the nose and kidney are often recognized in the ears in lung disease." "When you are sick, you can see the treatment of the five internal organs by observing its various shapes and colors, so you can tonify and reduce the diarrhea, which is wonderful." The above discussion shows that Wan attaches great importance to examination in the diagnosis and treatment of children's diseases.

Wan Mizhai emphasized the combination of "four diagnosis" and "home visits". For example, in the play Pediatrics, it is said that "seeing, listening and asking are also a great solution for doctors". "Children are different in size and the depth of the disease is different. Look at the difference between shape and color. If we can study it carefully, we can exhaust the sacred craft, and those who look at the cover can't tell the color. ..... The listener knows its symptoms; ..... The questioner asked the disease to investigate its origin; People who feel the pulse judge the disease. " When distinguishing between cold and heat deficiency and excess of a disease, it is emphasized that inspection should be combined with other diagnoses, and people who are really hot will blush when they meet, which is color excess; Pulse number, that is, pulse fullness; Constipation, yellow urine, thirst, shortness of breath, and fever in feet and calves are symptoms. Only the color, pulse and syndrome can be identified as excess-heat syndrome, which should be treated with cold and cool. However, white face, slightly heavy pulse, clear stool, abdominal distension, vomiting, cold feet and shin, color, pulse and deficiency of symptoms can be distinguished as deficiency-cold syndrome, which can be treated by warming and tonifying methods.

Judge the cause of treatment and pay attention to the spleen and stomach

Wan Mizhai put forward many new views on the etiology and pathology of common and frequently-occurring diseases in children. If Wan thinks that acute convulsion and slow convulsion are symptoms, it is necessary to check the cause. There are three reasons for acute convulsion: the external cause is the person who feels cold, damp and hot and loses treatment; Internal injuries, fever and lack of treatment are internal causes; Those who get evil from frightened guests are not solid inside and outside. In clinical manifestations, Wan's syndrome is divided into acute convulsion syndrome, including umbilical wind convulsion, diarrhea convulsion and so on. Acute convulsion syndrome refers to epilepsy syndrome caused by repeated convulsions; Distinguish nine suspected syndromes of acute convulsion, such as epilepsy caused by natural fishing and epilepsy caused by helminthiasis; It is the first time to put forward the sequelae of acute convulsion such as "epilepsy due to acute convulsion", "paralysis due to acute convulsion" and "speechless after acute convulsion" The detailed discussion greatly enriches the predecessors' theories and provides a theoretical basis for future generations' further research. He also has unique views on smallpox, measles and other diseases, such as the treatment of acne rash, which advocates "warming and cooling diarrhea, each with its own characteristics" and abandons the prejudice of previous doctors. Wan attaches great importance to the spleen and stomach in treatment, and uses drugs carefully but lightly.

"Pediatrics" emphasizes: "The stomach governs the reception, the spleen governs the transport, the spleen and stomach are strong, the limbs are safe, the spleen and stomach are weak, and all diseases are born. Regulating the spleen and stomach is also the king of medicine." "The method of conditioning is not limited to drugs, but only to wet nurses. Diet, careful medicine, so that the spleen and stomach are not hurt, it is often solid. " Children's spleen and stomach are most easily injured because of deficiency of qi and spleen, and diet, coldness and temperature can't be controlled. Wan Mizhai listed "frugal diet and careful medication" as the primary principle of children's health care and disease prevention. When treating a disease, it is advisable to "treat the disease mainly, and be careful not to get angry and hurt the stomach". In the medication, it is emphasized that "taking its flatulence and tonifying its diarrhea, especially avoiding cows, can not consume yin with stony heat and hurt the stomach with bitter cold and yang". Wei Ping Powder, Ling Wei Pill and Gong Yi Powder were commonly used in clinic, which opposed the abuse of clove and Amomum villosum at that time. All the medicines in Wan Mizhai are refined, and most of the prescriptions are handed down from family or made by themselves. Pills and powders are widely used in dosage forms, which are light and powerful and convenient for children to take. For example, "Wanshi Niuhuang Qingxin Pill" has become a classic of traditional Chinese medicine, and the thirteen ancestral prescriptions of Wanshi are also widely used in clinic. Wan Mizhai also advocated the application of massage, acupuncture, umbilical ironing, medicated bath and other external treatments to treat children's diseases.

Strict scholarship, law-abiding not muddy.

Wan Mizhai was rigorous in his studies all his life, realistic and not vain. Whether it is the theory of the former sages or the law of the ancestors, he has to practice it repeatedly before making a detailed discussion and never blindly following it. For example, the application of the thirteen prescriptions handed down from generation to generation is not only elaborated in "Prescription Science", but also listed a large number of medical records, which are clearly seen by future generations from theory to clinic. Wan's medical theory mostly inherits the predecessors' experience, obeys the treatise on febrile diseases, draws lessons from Danxi and Dongyuan School, and especially worships academic viewpoints, but is not superstitious and treats it with a pragmatic attitude. For example, in the Prescription for Children's Medicine, Beneficial Yellow Powder tonifies the spleen and stomach, which is sometimes effective for many people, but Wan thinks that "Beneficial Yellow Powder is too effective in treating spleen and stomach deficiency and cold, and it is also a strange medicine, and it is wrong to tonify spleen and stomach deficiency and cold".

Because the clove in the recipe is pungent and hot, the fire is stronger, and the soil is weaker. Green tangerine peel and tangerine peel diarrhea the lung, and the lung is the son of the spleen. In fact, the spleen has to diarrhea, so the spleen soil is weaker. Therefore, it is not advisable to use Yihuang Powder to tonify the spleen and stomach, but Gong Yi Powder should be used instead. Wan criticized the use of too many stones. In a word, Wan Mizhai not only summarized the theory and practice of TCM pediatrics since the Tang and Song Dynasties, but also developed TCM pediatrics with his own experience and made outstanding contributions to the cause of TCM pediatrics.

Wan Mizhai's works and academic thoughts are clean and pure, extensive and profound, involving children, women, internal medicine and eugenics, excellent education, age extension, dissemination, health preservation and health care. Looking back, because it is a bridge between the past and the future, it has had a far-reaching impact on clinical medicine in the Ming and Qing Dynasties. Looking forward to the future, because of its people-oriented, complete prescriptions, flexible treatment and strong practicability, it also has important reference value for theoretical research and clinical work of contemporary Chinese medicine, among which the famous ones are Wan's Female Family Branch, Literature Review, Gynecology Excerpt, Baby Health Care Tips, Heart Therapy of Vaccinia, Excerpt of Typhoid Fever and Song of Saving Life. Therefore, it is worthy of in-depth discussion and development for the benefit of all mankind.

Remote broadcasting of medical names

Wan Mizhai, a doctor, not only inherited the knowledge handed down from his family, but also inherited his father's teachings focusing on the Soviet Union and the South. He studied pulse meridians and materia medica, learned from Zhongjing, Hejian, Dongyuan and Danxi, and was proficient in internal medicine, gynecology, pediatrics and health preservation, especially in family pediatrics and acne rash. It is famous from Jiajing to Wanli. According to Wan Mizhai's medical records, his medical footprints are all over Luotian, Qishui, Yingshan, Macheng, Huanggang and other neighboring counties, as far away as Wuchang, Yunyang and even the capital, and countless people are alive. He is not only superb in medical skills, but also noble in medical ethics. He "takes the living as his heart", "takes the son of man as his own son" and "does not take advantage of the situation"; He denounced quack doctors for misleading people and opposed witch doctors for confusing people. He treats patients regardless of blood, feud, wealth and dignity, and sympathizes with their sufferings; When a sick family asked for treatment, he devoted himself to the rescue. When he meets a critically ill patient, he often guards him day and night, and sometimes stays at the patient's home for the New Year, which is deeply loved by people from all directions.

Wan Mizhai is a famous medical expert on par with Li Shizhen. In the Ming Dynasty, there was a saying that Wan Mizhai prescription was Li Shizhen medicine. Often invited by the county, the government, the Ministry of Foreign Affairs, and the governor to treat diseases. He was awarded the plaque of "Confucian doctor" twice by Zhu, the magistrate of Luotian County, and Sun, the minister of foreign affairs of Huguang County, and was called "imperial doctor" at that time. After his death, Emperor Kangxi of the Qing Dynasty made him a "medical sage". In the forty-seventh year of Kangxi (1708), Luotian County magistrate Shen Tingzhen personally rebuilt the tombstone and wrote an inscription. In the inscription, there are the words "the country sealed the medical sage", and the handwriting is clearly visible so far. During the Ming and Qing Dynasties, many doctors at home and abroad spoke highly of Wan. For example, physicians in the Qing Dynasty, Japan's Tommoto Qiushi, Danbo, North Korea's Xu Jun, etc., cited a large number of medical books in their works, such as Women and Children Zongcheng, Medicine, Miscellaneous Diseases, and Oriental Medical Collection. Japanese scholar Ikeda Rouxing quoted Wan's book The Essence of Argument. In addition, it is said that many books have not been printed. 1999 Wan Mizhai was listed as one of the top 30 famous doctors in Ming and Qing dynasties by the state, and The Complete Collection of Wan Mizhai Medicine was included in the series of Complete Collection of Famous Doctors in Ming and Qing Dynasties by China Medical Publishing House.