His family doctor, grandfather Lan, was born in (now Nanchang, Jiangxi), and became famous for his youth, but he regretted his early death. His father's name is Basket, and he is still a pediatrician after inheriting his ancestral home. Sixty years after Chenghua (1480), he went to Luotian because of the shortage of soldiers, married and had children, and settled in Luotian. He became famous in the first world war and was called Wan's pediatrics.

Wan Mizhai was originally a student, but after failing in the exam, he decided to study medicine. Because his family has been helping the world with "medicine" for generations, medicine has a deep family origin, and I am diligent in studying and summing up clinical experience, so his medical attainments are profound, especially in taking pulse and looking at color. Some difficult diseases can be clearly dialectical after his diagnosis. Especially in pediatrics, gynecology and internal medicine. In pediatrics, he summed up the three causes of children on the basis of thirteen aspects of family heirloom, and put forward the policy of not taking too much medicine and focusing on prevention, which is quite unique. In gynecology, he expounded the physiological and pathological characteristics of women, and pointed out that nourishing qi and blood and regulating spleen and stomach had a far-reaching influence in the history of gynecology of traditional Chinese medicine. The "Wan's Niuqingxin Pill" invented by him is still a good medicine for treating acute convulsions in children.

Wanquan treatment not only inherited family studies, but also studied the Pulse Classic and Materia Medica on the basis of Neijing and Nannan, betting on Zhongjing, Hejian, Dongyuan and Danxi, and also studied Neijing, Gynecology, Pediatrics and Health Preservation. His medical skill is getting better and better, which is very famous in Wanli period of Qin Long. Practice medicine all over Luotian, Qishui, Yingshan, Macheng, Huanggang and other places, as far away as Wuchang and Yunyang, and there are many living people. Everything is not only superb medical skills, but also very noble medical ethics. He denounced the quack doctor for misleading others, opposed the witch doctor's confusion, and pursued the principle of "old me, young me" and "treating other people's sons as his own". He treats diseases without remembering old grievances, sympathizes with the working masses, sends medicines to doctors, and is deeply loved by the people.

The county, the government, the Ministry of Foreign Affairs and even the governor and local officials at all levels often ask him to treat diseases. He was once told that the county and the Ministry of Foreign Affairs had given him a "Confucian doctor" plaque. In addition to clinical practice, he is diligent in writing, and most of the works handed down today were completed in his later years. Although Wanquan abandoned medicine and joined literature in his early years, his worship of Confucianism continued unabated. He opened the school library many times and taught students and apprentices without interruption. He also wrote a lot of Confucian works, claiming that "self-study history and calendar can catch hundreds of people, and each has his own works." Unfortunately, none of his Confucian works have been handed down. Wanquan's family background, he studied Neijing and Nanjing with theory and practice very early, and learned from various schools. His profound understanding of Confucianism is an important condition for his medical achievements.