Suggestion: Take traditional Chinese medicine to clear heart and soothe nerves, soothe nerves in important towns, invigorate qi and nourish blood, improve immunity, invigorate qi, strengthen spleen and regulate stomach. Psychoanalysis: Hello, according to the personal information you provided, it may be because you are sensitive and fragile, thoughtful, psychologically stressed and nervous, and you can't relax and calm before going to bed, which leads to insomnia, brain dysfunction, irritability and anxiety. It is a psychogenic problem of neurosis, which can be improved by formal psychotherapy. Long-term mental instability will lead to a variety of physical and mental diseases. Dietary supplements are only auxiliary, not the main therapeutic effect.
Psychological guidance: I suggest you go to the nearest regular Chinese medicine hospital for examination first, and choose symptomatic Chinese medicine to regulate body surface symptoms under the guidance of a doctor; At the same time, we should pay attention to the importance of psychological pathogenic factors, check and measure at the nearest formal psychotherapy institution in time, diagnose the nature and severity of current symptoms, and adjust and improve through formal psychotherapy. Usually keep the diet light and nutritious, and don't eat spicy food. Guidance: Hello, it is recommended to use vitamin B 1+ oryzanol+Anshen Bunao Liquid for adjustment and treatment under the guidance of a doctor. At the same time, be careful not to change your mood too much, and eat more foods rich in protein and trace elements. People are animals and belong to the same creature as plants. During the day (5: 00 am to 2 1 point), activities generate energy, and at night (2 1 point to 5: 00 am), cells start to divide and transform energy into new cells, which is the time for human cells to recuperate and innovate. It is also people who follow the earth to the side facing away from the sun. Yin governs quietness, which is a good time for people to sleep. Only by resting at this time can they have a good state of mind and body. This is the same reason that babies who sleep more grow fat and fast, and children who love to sleep are stunted.
Sleep is a major function of health preservation. Health preservation means replacing rotten cells with a large number of healthy cells. If you can't sleep all night, you can't replace new cells. If you say that one million cells die during the day and only 500,000 cells are replaced in one night, then your body will lose. After a long time, people will be chaff, just like chaff and radish. Why are there centenarians in the world? Because they go to bed on time at 2 1 every night. The purpose of operation is to restore the diameter of spinal canal, but the recovery of nerve paralyzed by compression depends on the promotion of drugs besides self-repair. Postoperative recovery was acceptable, but some nerves were still in a state of paralysis and shock. If the disease does not get the best recovery within the effective treatment range, the nerve may atrophy and soften due to long-term ischemia, and it is difficult to restore various functions at this time. Therefore, the key to treatment and recovery lies in early stage.
At present, in addition to neurotrophic drugs, spinal nerve regeneration pills can be used to excite and activate paralyzed and shocked nerve cells after injury, enhance intercellular conduction, and obtain the best recovery of limb function and defecation.
I wish you a speedy recovery! Lumbar surgery only restores the diameter of the spinal canal and creates favorable conditions for nerve recovery, but it can't restore nerves. In addition to self-repair, the nerve recovery of compression injury and paralysis depends on the promotion of drugs to obtain the best recovery state. If the disease can't get the best recovery within the effective treatment period, the nerve may atrophy, soften, degenerate or necrosis due to long ischemia time, and the recovery of the disease is hopeless. Therefore, the key to treatment and recovery lies in early stage. In addition to neurotrophic drugs, traditional Chinese medicine can also be used to strengthen and improve the damaged parts of nerves.
Nerve regeneration drugs were used to excite and activate those who were still paralyzed and shocked after operation.
To dominate the recovery and improvement of lower limb function. If you need help, please send a magnetic shock for guidance. 1, eat regularly, choose soft and chewy food, and eat it for patients with chewing pain.
Never eat fried food, irritating food, seafood products and
Wait; Diet should be nutritious, eat more vitamins and clear fire at ordinary times.
Food; Eat more fresh fruits, vegetables and beans, eat less fat and eat more lean meat, and the food should be light.
2, eat gargle, talk, brush your teeth, wash your face to be gentle, do not stimulate food, so as not to induce.
Caused by point
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3. Keep your head and face warm, avoid local freezing and humidity, and don't wash your face with too cold or too hot water; Usually, you should keep your mood stable, don't get excited, often listen to light music, feel calm and get enough sleep.
4. Stay happy and avoid mental stimulation; Try to avoid touching the "trigger point"; For a regular life, the indoor environment should be quiet, clean and fresh. Appropriate participation in sports, exercise, and enhance physical fitness. Let's talk about some professional drugs to repair nerve function, the first kind of nerve growth factor enhancer.
Powdered potassium Powdered potassium is a cognitive enhancer, which is used to treat mild and moderate Alzheimer's disease (AD). By increasing the level of neurotrophic growth factor in damaged or degenerated neurons, the function of nerve cells is enhanced, axon growth is stimulated, and memory ability is improved. This is the first drug to enter a phase III clinical trial to enhance nerve regeneration.
Acetyl L-Carnitine Acetyl L-Carnitine is a cholinergic agonist, which can actively cross the blood-brain barrier, protect the central and peripheral synapses, increase the level of nerve growth factor, and improve the cognitive defects of senile rats with neurodegeneration and aging models. Currently, it is conducting phase III clinical trials in the United States.
The second kind of neurotrophic drugs
Gangliosides (GM 1) Gangliosides can promote nerve remodeling (including nerve cell survival, axon elongation and synaptic growth), and play an important role in cell differentiation, development, nerve tissue repair and neuronal plasticity.
Brain protein hydrolysate is a new drug to improve brain metabolism, which easily enters brain nerve cells through the blood-brain barrier, affecting their protein synthesis and respiratory chain, enhancing the antioxidant capacity of brain cells, protecting the nervous system from toxic substances, delaying the death of brain cells and promoting their survival.
Cytidine disodium triphosphate injection is a kind of nucleotide drug, which can not only promote the synthesis of protein, but also regulate and promote the synthesis and construction of cell membrane structure of nerve cells, glial cells and blood vessel walls, and can resist the damage of excitatory amino acids and free radicals to nerve cells, thus having the functions of supporting survival, enhancing activity, delaying death, improving the ability of cell to resist injury and repair, promoting the regeneration of nerve axons, improving the nerve function innervating blood vessels, and resisting arteriosclerosis.
Oxiracetam Oxiracetam is a new central nervous system drug, which can promote learning and memory. Oxiracetam can selectively act on cerebral cortex and hippocampus to activate, protect or promote the functional recovery of nerve cells.
The third kind of drugs that destroy and inhibit axon growth
In the process of nerve injury repair, besides the factors that promote nerve growth, the factors that inhibit nerve growth should also be considered. Among them, mature oligodendrocytes can produce many axon growth inhibitory factors, and primitive oligodendrocytes can also shrink axon growth cones and inhibit axon extension.
Chondroitinase ABC(chABC) can decompose the glycosaminoglycan chain of chondroitin sulfate proteoglycan. Bradbury et al. found that after spinal cord injury, intraspinal administration of chABC can effectively promote axonal regeneration and improve motor and proprioception functions of rats. In the treatment of spinal cord injury, local injection of chABC can promote axonal regeneration and functional recovery. This discovery has a very attractive prospect in promoting the plasticity of adult central nervous system (CNS) and the recovery of nerve function.
Chondroitin sulfate proteoglycan also has neuroprotective effect. Further study on the regulation mechanism of extracellular matrix molecule expression in pathological state of central nervous system will provide new ideas for the study of central nervous system injury and repair. Weakening the inhibition of myelin axon growth is also an effective strategy to promote axon regeneration.
In addition, blocking Ngg, the receptor of myelin-related axon regeneration inhibition, is also an effective strategy, and cAMP, the second messenger, has also been found to weaken the inhibition of these factors.
The fourth category of antioxidants and energy metabolism drugs
Oxidative stress is related to the pathogenesis of many nervous system diseases, including Alzheimer's disease (AD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD) and Friedrich's ataxia (FRDA). Antioxidants and energy metabolism drugs have been used for neuroprotective treatment of many nervous system diseases.
Edaravone is a free radical scavenger and antioxidant. A large number of research results show that edaravone can inhibit the peroxidation of brain cells, thus reducing brain edema and tissue damage caused by cerebral ischemia and cerebral hypoxia, and is used for neuroprotective treatment of acute stroke.
Coenzyme Q 10 has two main functions: first, it plays an important role as a nutrient in the process of mitochondria transforming into energy; Second, it is obviously resistant to lipid peroxidation. The combination of coenzyme Q 10 and vitamin E can increase the productivity of heart and autonomic muscles in FRDA patients, and effectively reduce the dilated myocardium in FRDA patients.
Idebenone idebenone is an analogue of synthetic coenzyme Q 10, which can improve the neurological function of FRDA patients with good tolerance.
Creatine Creatine may improve mitochondrial dysfunction, stabilize mitochondrial function, protect neurons, reduce brain atrophy and the formation of nuclear inclusions in HD.
Selegiline Selegiline is a selective monoamine oxidase inhibitor, which can improve the cognitive ability of AD patients by increasing catecholamine, and is mainly used for mild to moderate AD. Selegiline has a certain neuroprotective effect and has been recommended as a neuroprotective drug by Parkinson's Disease Neuroprotective Committee.
LAX- 10 1 is an inhibitor of phospholipase and cysteine aspartic protease, which may enhance mitochondrial activity, and is currently preparing for phase III clinical trials.
The fifth kind of neurotransmitter drugs
Acetylcholinesterase inhibitors (AchEIs) such as tacrine, donepezil, rivastigmine and galanthamine have been approved by FDA for the treatment of mild and moderate AD. Donepezil can also improve the aphasia quotient index of patients with aphasia after stroke.
Nicotinic acetylcholine receptor agonists widely exist in the nervous system, which can improve the cognitive memory impairment of AD through various mechanisms. Stimulating nAChR can improve cognitive memory. Among the various selective nAChR agonists developed, some of them have entered the clinical trial stage, including GTS-2 1, ABT-4 18, nefixitan and so on.
Thyroid stimulating hormone releasing hormone (TRH) analogue TRH, as a neurotransmitter, can regulate other neurotransmitters and improve learning and memory. TRH analogues such as Montetirine, Azerotiline and Botuline have entered clinical trials.
L-dopa L-dopa can not only significantly improve the symptoms of patients, but also have neuroprotective effect, and increase the level of glutathione, which has neurotrophic effect.
Ritalin Ritalin combined with physical therapy can improve the motor function, relieve depression and improve the thinking activities of patients with brain injury, which is superior to the control group in attention and exercise.
Buspirone, a 5-HT receptor agonist, can significantly improve the stability, coordination, clarity and eye movement function of ataxia patients. Tandospirone is used to treat anxiety and depression, and can improve dysarthria and upper limb symptoms of ataxia patients.
As a new generation of antidepressants, 5-HT reuptake inhibitor (SSR 1) SSR 1 can block 5-HT reuptake, increase the availability of 5-HT in synaptic cleft, and thus enhance the nerve transmission of 5-HT. Fluoxetine is used to treat stroke patients with severe disability, and their walking function and daily living ability have been improved.
Reboxetine is a selective norepinephrine reuptake inhibitor (NRI) and a new antidepressant. In the clinical trial of treating patients with stroke sequelae, it is found that the tapping speed and grip strength of fingers have improved.
Memantine, an antagonist of N- methyl -D- aspartic acid (NMDA) receptor, is a non-competitive antagonist of NMDA receptor, which can prevent the development of AD by inhibiting NMDA receptor-mediated excitotoxicity. Memantine has neuroprotective effect, which is not only effective for mild AD, but also can significantly improve the clinical symptoms of severe dementia. Combined with acetylcholinesterase inhibitor, it can increase the curative effect and has good tolerance.
The sixth kind of anti-excitotoxic drugs
Riluzole is an excitatory amino acid receptor blocker with potential neuroprotective effect, and it is the only drug approved by FDA for clinical treatment of ALS. Riluzole has short-term anti-dancing effect and sustained mental movement speed and behavior in HD patients, but it has no obvious effect on delaying the progress of the disease.
Gabapentin is an inhibitor of glutamate synthesis and release, which can delay muscle weakness and prolong the survival time of patients with amyotrophic lateral sclerosis. However, the results of the third phase clinical trial showed that there was no significant difference between the treatment group and the control group. The main cause of cortical cerebellar atrophy is the loss of Purkinje cells in the anterior vermis of cerebellum, which reduces the concentration of GABA in tissues. Gabapentin can effectively relieve cerebellar symptoms.
Lamotrigine is a drug, which can inhibit the release of glutamic acid and aspartic acid, temporarily improve the symptoms of ALS, delay the progress of the disease and improve the abnormal walking of SCA3 patients.
The seventh class of other drugs
The study of lithium carbonate found that lithium has neurotrophic and neuroprotective effects, protecting granular cells in cerebral cortex, hippocampus and cerebellum. Animal and clinical studies show that lithium can be used to intervene acute brain injury (such as ischemia), spinal cord injury and chronic neurodegenerative diseases (such as AD, PD, HD, etc.). ).
Statins are the key enzyme inhibitors of cholesterol synthesis in mevalonate pathway, which can reduce the cholesterol content in the body, not only significantly reduce the incidence of ischemic stroke in patients with coronary heart disease, but also have neuroprotective effects independent of their lipid-lowering effects and reduce the occurrence of dementia.
Erythropoietin (EPO) EPO is a neuroprotective or (and) nerve repair drug that has attracted much attention in recent years. In addition to hematopoiesis, there is also a protective effect of the nervous system. Nerve regeneration factor, mecobalamin, vitamins and other drugs for the treatment of nerve injury should only be treated early. If it is early, the combination of medicine+acupuncture+hyperbaric oxygen is the best. Oryzanol, Mecobalamin, Vitamin B 1, Vitamin B 12.