A 60-year-old man's feet hurt when he walked. He thought it was degenerative arthritis, and then he limped, even his limbs turned cold and purple, and the wound of his foot ulcer lasted for a long time. After the doctor diagnosed the arterial obstruction of the lower extremity, he treated it in time to avoid the fate of amputation caused by the wound deterioration. Not just the heart! Limbs can also be blocked by blood vessels. Dr. Yang Weishun, from the Department of Nephrology, Hsinchu Branch of National Taiwan University Hospital, said that blood vessels in all parts of the body may be blocked, not just the heart or brain. If vascular occlusion occurs in four limbs (usually the risk of lower limbs is higher than that of upper limbs), it is called peripheral arterial occlusion. The sudden drop of temperature is easy to cause contraction of peripheral blood vessels, so peripheral artery occlusion often worsens rapidly in cold days. Dr. Yang Weishun pointed out that the initial symptoms of peripheral arterial occlusive disease are not obvious. After walking for a certain distance, the patient had to take a short rest because of the occlusion of the lower extremity artery and the aggravation of muscle hypoxia to ease walking again. However, the elderly often think that it is caused by degenerative arthritis of knee joint and stroke, so they ignore the early symptoms of peripheral arterial occlusive disease. Neglect of treatment can lead to severe shock. At this point, the muscle tissue of the limb begins to be ischemic and necrotic, and the affected area will first become pale, cold and painful, and may be accompanied by numbness and abnormal sensation. If you don't intervene immediately to open blood vessels, the tissue will start to turn dark purple or even merge with blisters or blood bubbles, and finally it will be completely necrotic and black, and the necrotic limbs such as toes will even fall off automatically. Necrotic tissue often causes inflammatory reaction, and even leads to infection and septic shock in severe cases. It is also important to control the "three highs" and "three highs" and quit smoking. Dr. Yang Weishun appealed that prevention of peripheral arterial occlusive disease is far more important than emergency treatment after onset. In addition to controlling the "three highs" (hypertension, hyperglycemia and hyperlipidemia), it is also important to quit smoking, because the probability of drug addicts suffering from peripheral arterial occlusive disease is three to seventeen times that of non-smokers. For high-risk groups, such as renal dialysis patients, we should pay attention to keeping the distal end warm in winter to avoid excessive contraction of blood vessels, and pay attention to the diet control of blood calcium and phosphorus in peacetime to avoid calcium and phosphorus precipitation in blood vessels causing calcification and stenosis of blood vessels and aggravating the degree of arterial obstruction. Subscribe to the health Aloha audio-visual channel, read health knowledge more easily, and pay attention to your health every day! Line @ ID: @:/supply/article/24087/Men's foot pain can't be ignored. Key words: lower extremity arterial occlusion, intermittent claudication, muscle tissue, three highs, Hsinchu Branch of National Taiwan University Hospital, Yang Weishun.