With these questions, I conducted a thorough investigation on nmn!
After checking a circle of data, it turns out that NAD+ in our body is not anti-aging, but the precursor nmn of NAD+, because the molecular weight of NAD+ is too large to be absorbed by the body through external donation. In fact, nmn and NAD+ are endogenous substances in human body. But when people are over 30 years old, the secretion of these substances will gradually decrease, which is why our skin will get worse and worse with age, and our body parts will become more and more useless! Why NMN can resist aging will be explained in detail in the next article!
According to the data, NMN has won many Nobel Prizes, which can really help anti-aging and even prolong life. However, due to the uneven products on the market, we are afraid to disturb your choice. We have also formulated ten international core standards for NMN quality management. Whether you choose Hong Kong nmn9000 or ACMETEA W+nmn certified by two countries, you must follow the top ten international core standards of NMN quality management! In fact, you can rest assured with the standard, right?
Sister Le first talked about what are the top ten international core standards of NMN quality management, which made the sisters have a foundation in their hearts and were wasted. The result didn't play any role:
Sister le is not easy to tidy up, so you should look carefully. If you have time, you can also praise it with your rich little hands:
Ten International Core Standards of NMN Quality Management
1. Quality management system: NMN must meet the inspection qualification of OULF EU law and the certification of FDA, US Food and Drug Administration. In addition to the product name, all ingredients and NMN purity should be indicated, and the country of origin and distribution should be indicated.
2. Manufacturing process management system: Advanced manufacturing process affects the shape of NMN. Chemical extraction is not recommended to avoid chemical residue.
3. Content management system: the relative NMN content is ≥ 12000 mg/ bottle, which is directly absorbed into the small intestine, and the intestinal absorption is 20% of the gastric absorption.
4. Efficiency management system: the authenticity and purity of raw materials should be investigated.
Absorption management system: adopt intestinal absorption to improve absorption rate and absorption threshold.
6. Activity management system: The unit dose (per 100g) is converted into the number of molecules of NAD+, and NMN molecules can easily cross the cell membrane and enter the cell interior, thus increasing the human NMN content within 15 minutes and rapidly raising the level of NAD+.
7. Application scope of management system: adults (pregnant women and lactating women are prohibited).
8. Safety management system: production technology, raw material collection, basic system of Olaf safety standards, pre-factory safety inspection, strict review of microbial heavy metals exceeding the standard, and scientific production technology.
9. Raw material management system: Most NMN enterprises are certified by a single country, but at present, the management of raw materials certified by two countries is more rigorous and safe, such as ACMETEA W+NMN, which belongs to the products certified by France and the United States.
10, transnational regulatory management system: dual supervision of "law" and "beauty". The FDA of the United States has established GMP standards for dietary supplements, and the EFSA of the European Union also has relevant regulations on the management of food supplements.
Good standards have been given, and sisters can look at them carefully and refer to them carefully! Let's first introduce what nmn is. Why can it resist aging? The content is a bit long, but I will thicken the key content and omit your precious time!
What is nmn?
It should be explained in advance here, because NAD+ cannot be directly absorbed by the body, so supplementing nmn from outside can promote the secretion of NAD+, thus achieving anti-aging effect!
So I will introduce the role of NAD+ in the body and explain what nmn is and its role in the body.
Let's start with Sister Le:
NAD+ is indeed a key and industrious coenzyme in human body. Widely distributed in all cells of human body, it participates in thousands of biocatalytic reactions and is an essential coenzyme for human body. NAD+ has many functions in the body. Today, I only talk about anti-aging.
When you talk about thousands of reactions, you may not know. What are the important reactions of NAD+ participation? What is related to human aging? First, let's look at the familiar tricarboxylic acid cycle:
As we can see in the figure, NAD+ plays a very important role in the tricarboxylic acid cycle (popular science tricarboxylic acid cycle: in short, we can have the strength and state of being alive now, which is dominated by the energy after the tricarboxylic acid cycle).
In the tricarboxylic acid cycle, the increase of NAD+ can promote the above process, thus adjusting the rate of energy production. On the contrary, if the body lacks NAD+, the circulation will not go smoothly, and mitochondria will not be able to efficiently convert the food we eat into the energy needed by the human body, which will lead to aging. You got it! However, after the age of 30, human body functions will show a downward trend, we will gradually get older, wrinkles will appear on our faces, and our body resistance will decline. In order to change this state, NAD+ must be supplemented to make it sufficient, but NAD+ molecules are too large to be directly supplemented, so nmn, the premise substance of NAD+, must be supplemented to achieve the purpose of anti-aging!
After writing this paragraph, Sister Le's brain cells really don't know how many died, which I summarized in my own way by consulting a lot of literature. Please cherish!
All right! Sister Le has sorted out what nmn is and why it can resist aging. Sisters who like me want to keep their looks or grow old slowly will be curious about what to do when shopping.
Careful Lejie also sorted out the details of the top ten core standards for choosing NMN.
Details of ten international core standards of NMN quality management:
A, quality management system:
First of all, NMN must meet the requirements of "OULF" EU law and "FDA, US Food and Drug Administration" certification. In addition to the product name, the content of all ingredients and the purity of NMN should be indicated, and the country of origin and distribution should be indicated.
Second, the production process management system:
Will the manufacturing process also affect the health of MNM?
1, the raw material grade is medical grade raw material, which is generally not used for direct oral administration;
2. Because I chose ACMETEA W+NMN, I know it very well. Its "cold-pressed biological enzyme" production technology can keep NMN alive at low temperature and press it into stable capsules, which can improve the purity of NMN to 99%, which is more conducive to preservation and human absorption, thus maximizing the bioavailability of cofactors and supporting human metabolism without SLC 12A8.
Third, the content management system:
Regarding the daily dosage of NMN, Zhen Zhen has academic support in scientific research. It is said that the human dose is 8 mg NMN per kilogram of body weight every day. If converted into 70 kg adults, the recommended daily dose is about 560 mg. Considering the daily absorption, consumption and aging, the content of ACMETEA W+NMN is ≥ 1200 mg/ bottle.
At present, the total content of NMN in each bottle is different. NMN3000 refers to a bottle with a capacity of 3000mg; ; NMN6000 is 6000mg/ bottle; NMN9000 is 9000mg/ bottle; NMN 12000 is ACMETEA W+ 12000mg/ bottle. At present, ACMETEA W+NMN 12000 has the highest content and purity. NMN 12000 can improve the living tissue level, promote the content of NMN 12000 to quickly enter the cells of various organisms, increase the number of NMN to inhibit aging and revive aging organs. Our body is gradually losing its function and repairing it in time. Successfully revived the cells. That's why I chose it!
Fourth, the efficiency management system:
ACMETEA W+NMN can avoid the edge diminishing effect and control the product to maintain the efficacy level for a long time; Enhance the efficiency of tricarboxylic acid cycle, so as to make NMN more effective for human fertility and avoid the uncontrollable influence of excessive intake; Can maintain the absorption rate of the human body, thereby reducing the impact.
Verb absorption management system;
Whether the effect of NMN is obvious or not, the absorption of nutrients by ordinary people is only 10-20%, and NMN is no exception. When the purity of NMN is increased to 99%, ACMETEA W+NMN technology can stabilize the morphology of MNM in the stomach, quickly penetrate the membrane to avoid gastric acid damage, and the absorption rate can be increased by ten to twenty times. Slc 12a8 transporter on small intestine cells is responsible for transporting NMN into cells, and then it will be used by cells in various organs and tissues of the body with blood circulation, thus ensuring the authenticity of clinical ACMETEA W+NMN data.
Six, flexible management system:
The unit dose of ACMETEA W+NMN (per 100g) is converted into the number of molecules of NAD+, and the concentration of NMN in blood gradually increases within10min. Within 30min, NMN enters multiple tissues with blood circulation, and NAD+ is synthesized in tissues, thus increasing the level of NAD+.
Seven, the scope of use of management system:
1. elderly people, used to help improve various senile diseases;
2. Middle-aged people, eliminate or alleviate various sub-health problems, such as chronic fatigue, poor sleep, and decreased vision. ;
3. Stay up late, accelerate physical recovery;
4. Candidates should improve their ability to resist pressure and keep a clear head;
5. Those with higher radiation dose, such as radiologists, nurses and aircrew, improve their ability to repair genes damaged by radiation;
6. Cancer patients, help patients repair genes after radiotherapy and chemotherapy, improve immunity and accelerate physical recovery;
7. Fitness to accelerate muscle growth;
8. Athletes, improve their energy level and reaction speed;
9. drinkers, improve the ability to sober up, protect the liver and repair the genes damaged by acetaldehyde toxicity;
10. Smokers, reduce smoking addiction;
1 1. Patients with depression can increase dopamine level, improve mood, increase blood supply to the brain, and alleviate brain decline caused by depression;
12. Middle-aged and elderly women can improve skin health and delay skin aging;
Eight, safety management system:
In terms of production technology, the purity of extracted NMN is as high as 99% and the content of each bottle is as high as 12000mg by ACMETEA W+NMN "cold pressed biological enzyme" production technology. ACMETEA W+NMN is also the highest content among NMN brands at present. The basic system of OULF EU safety standards strictly abides by the factory safety inspection, strictly examines the microbial heavy metals exceeding the standard, and scientifically extends the production technology.
Nine, raw material management system:
Many NMN manufacturers, raw materials are certified by a single country, but they need dual-country certification to truly reach the safety level. At present, ACMETEA W+NMN products belong to French and American certification standards. In terms of raw materials, it has reached strict and safe management standards.
X. Safety management system:
ACMETEA W+NMN meets the requirements of FDA for dietary supplement GMP. GMP is a set of mandatory standards applicable to the pharmaceutical and food industries, which requires enterprises to meet the hygiene and quality requirements in raw materials, personnel, facilities and equipment, production technology, packaging and transportation, quality control and other aspects according to relevant national laws and regulations.
ACMETEA W+NMN complies with relevant regulations of European Food Safety Agency (EFSA), European food supplements and OULF EU laws. The purpose is to ensure that the nutrition and health information provided to consumers on food packaging is accurate and reliable, so as to avoid misunderstanding by consumers. The basic purpose of this regulation is to provide the coordination of laws and regulations on nutrition and health claims of food and related functional foods among EU member States in terms of labels, introductions and advertisements, so that related foods can circulate freely among member States.
At the junior college level, it is really not easy to sort out these ten items. I feel a lot of hair loss after finishing! However, as a girl who loves beauty and wants to stay young, these values are commendable. I hope this article can help you, but Sister Le also wants to tell you at the end that there are many varieties of NMN on the market, but no matter which one you choose in the end, the top ten international core standards of NMN quality management must be met first! Remember this! That's it, ladies who have time can give me a compliment with your ridiculous little hands and leave!