Facial edema or edema is often caused by acute and chronic nephritis. At the initial stage, eyelid edema and severe ankle edema may appear first, not only facial edema, but also systemic edema. Pertussis, thoracic and mediastinal tumors, aortic arch aneurysms, long-term use of adrenal hormones, and occasional facial swelling when adrenal function decreases.

So it's best to persuade her to go to the hospital for examination!