Yes, it will mainly affect the function of your testicles, especially your ability to secrete testosterone. When the testis reaches a normal peak in normal blood, it will feed back to the pituitary gland, and the pituitary gland will stop releasing gonadotropins. If serum testosterone is insufficient, gonadotropin will be released, which will promote the release of testosterone from testis. If external testosterone is used instead of your own, testicular function will be reduced. This is what people call dependence.