Fatigue wrist pain generally depends on the severity of wrist pain and injury, and different treatment methods can often be adopted in clinic. First, the wrist works for a long time, accompanied by the accumulation of more metabolic wastes such as lactic acid, causing local soreness. At this time, it is suggested that adequate rest, proper massage, physical therapy and external application of wrist hot bag can promote the rapid absorption of metabolic wastes such as local lactic acid, thus alleviating pain symptoms. Second, if the ligaments and muscles at the wrist are strained due to overwork, it will cause obvious local swelling and limited activity. At this time, local ice can be given to promote capillary contraction and avoid the progressive aggravation of local swelling and pain symptoms. Combined with infrared radiation physiotherapy, external application of Huoxue Huayu ointment, oral administration of Zhitongan and other drugs can alleviate the symptoms of local joint swelling and pain and promote the rapid recovery of local injuries.