Human fat cells secrete a substance called leptin to keep people's weight balance.
Under normal circumstances, when you gain weight, fat cells secrete leptin, which is actually a messenger. It will send a message to the brain center, telling the brain that "there is a little more energy recently, so don't eat so much recently", and then the brain will make people's appetite worse through neural regulation, thus reducing energy intake and maintaining weight balance.
So for fat people, is it possible to lose weight by supplementing some thin elements? Experiments show that the method of adding leptin to lose weight has a very low success rate! Because for many obese people, their bodies are resistant to leptin! In other words, the natural body weight balance mechanism has been broken. When people eat a lot, fat secretes leptin, but it can't communicate effectively with leptin receptors in brain cells. As a result, the brain doesn't receive feedback that you need to fast, so the brain won't give orders to fast! If you have a big appetite, you will eat more energy than you need and get fatter and fatter, which will aggravate leptin resistance!
Many people have difficulty in losing weight, but they have actually entered a vicious circle of leptin resistance!
Then, for obese people with leptin resistance, if they want to lose weight, they can't use pure energy theory to lose weight. First, you must solve the problem of leptin resistance!