hereditary factor
1 type or type 2 diabetes mellitus has obvious genetic heterogeneity. Diabetes has a tendency of family onset. 1/4 ~ 1/2 patients have a family history of diabetes. At least 60 genetic syndromes can be associated with diabetes. There are many DNA loci involved in the pathogenesis of 1 diabetes, among which the polymorphism of DQ locus of HLA antigen gene is the most closely related. Many obvious gene mutations have been found in type 2 diabetes, such as insulin gene, insulin receptor gene, glucokinase gene and mitochondrial gene.
environmental factor
Obesity caused by overeating and decreased physical activity are the most important environmental factors of type 2 diabetes, which makes individuals with genetic susceptibility to type 2 diabetes prone to illness. 1 The immune system of diabetic patients is abnormal. After being infected by Coxsackie virus, rubella virus, parotid virus and other viruses, it leads to autoimmune reaction and destroys insulin β cells.
How did diabetes come from?
1. Bad living habits and eating styles. Nowadays, most young people prefer fast food like KFC to vegetables and fruits. Long-term bad eating habits can easily lead to high blood sugar.
2. "Negative oxygen ions", a natural factor existing in the air, can effectively reduce hyperglycemia, but with the pollution of the environment, the temperature changes abnormally. As a result, the content of negative oxygen ions in the air is greatly reduced, the negative oxygen ions absorbed by the human body are insufficient, and the ability of blood transportation to balance the sugar in the body is reduced, which is also an important cause of hyperglycemia.
3. Hyperglycemia caused by other diseases. Coronary heart disease and cerebral infarction are closely related to hyperglycemia. Therefore, once diagnosed as hyperglycemia, we should try our best to understand what causes hyperglycemia, so as to prescribe the right medicine and do a good job in the prevention and treatment of hyperglycemia.
Therefore, the change of diet structure (the increase in the proportion of carbohydrates such as main sugar), because the development of science and technology brings convenience to life, also reduces the amount of human exercise, increases the proportion of obese people, increases the burden of islet metabolism, and makes islet function more easily damaged.