There is a mass on the side of the neck, so the neck should be examined by ultrasound, because the common local lymph node enlargement will lead to the reactive proliferation of local lymph nodes during upper respiratory tract infection or oral and maxillofacial infection and inflammation, and the symptoms can be gradually improved after systemic anti-inflammatory and antiviral treatment. In addition, some patients are caused by tumors, including nasopharyngeal tumors and malignant tumors of respiratory system or digestive system, which are easy to transfer to the neck or supraclavicular region, and patients will have obvious abdominal pain, abdominal distension and abnormal defecation. Chest CT, gastroscopy and colonoscopy should be carried out in time, and biopsy can be removed if necessary. According to the pathological type, we can choose systemic intravenous chemotherapy or local radiotherapy to control the development of the disease.