Common women of childbearing age are naturally relieved after menopause. The main symptom of breast nodules is periodic breast pain. At first, it was diffuse swelling pain, and the tenderness in the middle and upper part of the breast was obvious. Every month, the pain before menstruation is aggravated, and the pain after menstruation is relieved or disappeared. Severe cases have persistent pain after menstruation. Sometimes the pain radiates to armpits, shoulders and backs, upper limbs, etc. Patients often report breast lumps, but only the thickened breast is felt during clinical examination. Very few adolescent patients with simple lobular hyperplasia of breast can heal themselves in about 2 years, and most of them need treatment. Then, experts from Harbin Maria Maternity Hospital said that the early symptoms of breast nodules are mainly manifested in the following two aspects: First, breast pain: common for unilateral or bilateral breast pain or tenderness. The course of the disease ranges from 2 months to several years, and most patients have the characteristics of periodic pain, which appears or aggravates in the pre-menstrual period and relieves or disappears after menstruation. It must be noted that although the periodicity of breast pain is a typical manifestation of this disease, people who lack this feature cannot deny the existence of this disease. Second, breast lumps: the early symptoms of breast nodules are often multiple, unilateral or bilateral, and more common in the above quadrants; And the size and texture often change with menstrual cycle. The premenstrual mass is enlarged and the texture is hard. After menstruation, the lump shrinks and the texture is tough but not hard. During palpation, palpable masses are nodular in structure, with different sizes, unclear boundaries with surrounding tissues, tenderness, no adhesion with skin and deep tissues, and no swelling of axillary lymph nodes.